Matches in SemOpenAlex for { <https://semopenalex.org/work/W31329354> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W31329354 endingPage "33" @default.
- W31329354 startingPage "27" @default.
- W31329354 abstract "Postoperative nausea and vomiting (PONV) is prevalent in surgical patients with known risk factors: general anesthesia, female, nonsmoker, motion sickness history, and PONV history. Common treatment involves ondansetron; however, the effects are short-lived, and supplemental medication may be required. Meclizine, a long-acting drug with a low side-effect profile, may be ideal in combination with ondansetron for at-risk patients. We randomized 77 subjects scheduled for general anesthesia and screened for 4 of 5 PONV risk factors for experimental or control group assignment. Severity of PONV was measured using a 0 to 10 verbal numeric rating scale (VNRS). Other measured variables included time to onset and incidence of PONV and total antiemetic requirements. No significant differences in demographics (excluding weight), surgical or anesthesia time, analgesic requirements, or nausea incidence in the postanesthesia care unit (PACU) and same-day surgery unit were noted. The meclizine group had lower VNRS scores in the PACU at 15 (P = .013) and 45 (P = .006) minutes following rescue treatment. The incidence of nausea was lower in the meclizine vs. placebo group (10% vs. 29%) following discharge (P = .038). Prophylactic meclizine resulted in lower incidence and severity of PONV in a high-risk population, especially after rescue treatment." @default.
- W31329354 created "2016-06-24" @default.
- W31329354 creator A5039681120 @default.
- W31329354 creator A5043591451 @default.
- W31329354 creator A5048674179 @default.
- W31329354 creator A5067133218 @default.
- W31329354 creator A5083295662 @default.
- W31329354 date "2007-02-01" @default.
- W31329354 modified "2023-09-23" @default.
- W31329354 title "Meclizine in combination with ondansetron for prevention of postoperative nausea and vomiting in a high-risk population." @default.
- W31329354 cites W2076484550 @default.
- W31329354 cites W2131111582 @default.
- W31329354 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17304780" @default.
- W31329354 hasPublicationYear "2007" @default.
- W31329354 type Work @default.
- W31329354 sameAs 31329354 @default.
- W31329354 citedByCount "3" @default.
- W31329354 countsByYear W313293542015 @default.
- W31329354 countsByYear W313293542020 @default.
- W31329354 crossrefType "journal-article" @default.
- W31329354 hasAuthorship W31329354A5039681120 @default.
- W31329354 hasAuthorship W31329354A5043591451 @default.
- W31329354 hasAuthorship W31329354A5048674179 @default.
- W31329354 hasAuthorship W31329354A5067133218 @default.
- W31329354 hasAuthorship W31329354A5083295662 @default.
- W31329354 hasConcept C120665830 @default.
- W31329354 hasConcept C121332964 @default.
- W31329354 hasConcept C141071460 @default.
- W31329354 hasConcept C142724271 @default.
- W31329354 hasConcept C204787440 @default.
- W31329354 hasConcept C27081682 @default.
- W31329354 hasConcept C2777170512 @default.
- W31329354 hasConcept C2777297131 @default.
- W31329354 hasConcept C2777395641 @default.
- W31329354 hasConcept C2780580376 @default.
- W31329354 hasConcept C2780852908 @default.
- W31329354 hasConcept C2780884295 @default.
- W31329354 hasConcept C2908647359 @default.
- W31329354 hasConcept C42219234 @default.
- W31329354 hasConcept C61511704 @default.
- W31329354 hasConcept C71924100 @default.
- W31329354 hasConcept C99454951 @default.
- W31329354 hasConceptScore W31329354C120665830 @default.
- W31329354 hasConceptScore W31329354C121332964 @default.
- W31329354 hasConceptScore W31329354C141071460 @default.
- W31329354 hasConceptScore W31329354C142724271 @default.
- W31329354 hasConceptScore W31329354C204787440 @default.
- W31329354 hasConceptScore W31329354C27081682 @default.
- W31329354 hasConceptScore W31329354C2777170512 @default.
- W31329354 hasConceptScore W31329354C2777297131 @default.
- W31329354 hasConceptScore W31329354C2777395641 @default.
- W31329354 hasConceptScore W31329354C2780580376 @default.
- W31329354 hasConceptScore W31329354C2780852908 @default.
- W31329354 hasConceptScore W31329354C2780884295 @default.
- W31329354 hasConceptScore W31329354C2908647359 @default.
- W31329354 hasConceptScore W31329354C42219234 @default.
- W31329354 hasConceptScore W31329354C61511704 @default.
- W31329354 hasConceptScore W31329354C71924100 @default.
- W31329354 hasConceptScore W31329354C99454951 @default.
- W31329354 hasIssue "1" @default.
- W31329354 hasLocation W313293541 @default.
- W31329354 hasOpenAccess W31329354 @default.
- W31329354 hasPrimaryLocation W313293541 @default.
- W31329354 hasRelatedWork W1970949300 @default.
- W31329354 hasRelatedWork W2025376021 @default.
- W31329354 hasRelatedWork W2027206415 @default.
- W31329354 hasRelatedWork W2072847349 @default.
- W31329354 hasRelatedWork W2073345208 @default.
- W31329354 hasRelatedWork W2112107129 @default.
- W31329354 hasRelatedWork W2125005452 @default.
- W31329354 hasRelatedWork W2152461367 @default.
- W31329354 hasRelatedWork W2406473905 @default.
- W31329354 hasRelatedWork W2412730153 @default.
- W31329354 hasRelatedWork W2415874375 @default.
- W31329354 hasRelatedWork W2417850643 @default.
- W31329354 hasRelatedWork W2597729024 @default.
- W31329354 hasRelatedWork W2783659979 @default.
- W31329354 hasRelatedWork W2899973888 @default.
- W31329354 hasRelatedWork W2909338313 @default.
- W31329354 hasRelatedWork W2981715483 @default.
- W31329354 hasRelatedWork W3011416920 @default.
- W31329354 hasRelatedWork W3133834566 @default.
- W31329354 hasRelatedWork W4225556501 @default.
- W31329354 hasVolume "75" @default.
- W31329354 isParatext "false" @default.
- W31329354 isRetracted "false" @default.
- W31329354 magId "31329354" @default.
- W31329354 workType "article" @default.