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- W3132958312 abstract "ABSTRACTPurpose To quantify the optic nerve head (ONH) and peripapillary retinal nerve fiber layer (pRNFL) thickness in patients with Coronavirus Disease-2019 (COVID-19) and compare the measurements with a healthy control group.Methods In a comparative cross-sectional observational study, ONH and pRNFL thickness were evaluated in patients with a history of COVID-19, at least 2 weeks after recovery from the systemic disease, and compared with an age-matched, normal control group.Results Thirty COVID-19 patients along with 60 age- and gender-matched healthy controls were studied. Mean average pRNFL thickness was 105.0 ± 16.3 µm in the COVID-19 patients, compared to 99.0 ± 9.0 µm in the controls (p = .31). The pRNFL thicknesses in all sectors was higher in patients with a history of COVID-19; however, this did not reach statistical significance. Similarly, ONH parameters were not significantly different between the groups.Conclusion Patients recovered from COVID-19 had unremarkable alterations in the peripapillary RNFL thickness.Abbreviations ONH: Optic Nerve HeadRNFL: Retinal Nerve Fiber LayerSD-OCT: Spectral-Domain Optical Coherence TomographyCOVID-19: Coronavirus Disease 2019SARS-CoV-2: Severe Acute Respiratory Syndrome Coronavirus 2CNS: Central Nervous SystemACE: Angiotensin-Converting EnzymeRT-PCR: Reverse Transcription-Polymerase Chain ReactionKEYWORDS: Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Optical Coherence Tomography (OCT)optic nerve headoptic discretinal nerve fiber layer AcknowledgmentsThe authors would like to thank Azam Sadat Salehnezhad at Khatam Eye Hospital, Mashhad, Iran. It is a pleasure for us to also acknowledge the kind supports of Mr. Yazdan Karimi. Financial disclosureThe authors declared no potential conflicts of interest for the research, authorship, and/or publication of this article.Additional informationFundingThe authors would like to acknowledge the financial support of the Vice-Chancellor of Research of Mashhad University of Medical Sciences for this research project [990069]. The funding organization had no role in the design or conduct of this research." @default.
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- W3132958312 date "2021-02-19" @default.
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- W3132958312 title "Optic Nerve Head Parameters and Peripapillary Retinal Nerve Fiber Layer Thickness in Patients with Coronavirus Disease 2019" @default.
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- W3132958312 doi "https://doi.org/10.1080/09273948.2020.1850800" @default.
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