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• W3132961529 startingPage "91" @default.
• W3132961529 abstract "This chapter initially provides a brief overview of current knowledge of neutrophil biology, providing background knowledge. It then examines neutrophil contributions to endometrial remodeling during the normal menstrual cycle, menstruation, and subsequent endometrial repair. This is followed by discussion of what is known of neutrophil contributions to placental development, parturition, and maternal immunotolerance. Finally, it examines how disturbances in neutrophil trafficking and phenotype may contribute to disorders such as abnormal uterine bleeding, pre-eclampsia, antiphospholipid syndrome and preterm birth. Importantly, the chapter highlights that while neutrophils predominantly act in concert with other immune cell types as part of the inflammatory cascade, neutrophils also perform specific independent physiological processes within the female reproductive tract. These independent processes are facilitated via release of inflammatory mediators, proteases, extracellular vesicles, and neutrophil traps released into the local tissue microenvironment, which interact with a variety of nonimmune cell types within the local milieu." @default.
• W3132961529 created "2021-03-01" @default.
• W3132961529 creator A5040346731 @default.
• W3132961529 creator A5046840933 @default.
• W3132961529 creator A5087119634 @default.
• W3132961529 date "2021-01-01" @default.
• W3132961529 modified "2023-10-18" @default.
• W3132961529 title "Neutrophils: Diverse functions in the endometrium of cycling women and during pregnancy" @default.
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