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- W3133017262 abstract "Generation of induced photoreceptors (PRs) holds promise as a tool for in vitro modeling of inherited retinal diseases. Direct reprogramming, direct conversion or redirect differentiation of somatic cells by overexpression of transcription factors is a promising, simple, and low-cost approach to generate target cells from somatic cells without using induced pluripotent stem cells. My research group has successfully generated PR-like cells from human somatic cells; iris cells, dermal fibroblasts, and peripheral blood mononuclear cells (PBMCs) using this redirect differentiation technique. In this chapter, I introduce this method and demonstrate its application as a cellular model of inherited retinal diseases." @default.
- W3133017262 created "2021-03-01" @default.
- W3133017262 creator A5076239285 @default.
- W3133017262 date "2021-01-01" @default.
- W3133017262 modified "2023-09-23" @default.
- W3133017262 title "Generation and Analysis of Induced Photoreceptor-Like Cells from Fibroblasts of Patients with Retinitis Pigmentosa" @default.
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- W3133017262 doi "https://doi.org/10.1007/978-981-15-9184-6_13" @default.
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