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- W3133056128 abstract "Photoacoustic imaging (PAI) is a novel hybrid imaging technique that combines the advantages of optical and ultrasound imaging to produce hyperspectral images of the tissue. The feasibility of measuring oxygen saturation (sO 2 ) with PAI has been demonstrated pre-clinically, but has limited use in humans under conditions of ischemia and reperfusion. As an important step towards making PAI clinically available, we present a study in which PAI was used to estimate the spatial distribution of sO 2 in vivo during and after occlusion of the finger of eight healthy volunteers. The results were compared with a commercial oxygen saturation monitor based on diffuse reflectance spectroscopy. We here describe the capability of PAI to provide spatially resolved picture of the evolution of sO 2 during ischemia following vascular occlusion of a finger, demonstrating the clinical viability of PAI as a non-invasive diagnostic tool for diseases indicated by impaired microvascularization." @default.
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- W3133056128 date "2021-03-30" @default.
- W3133056128 modified "2023-09-27" @default.
- W3133056128 title "Photoacoustic imaging of the spatial distribution of oxygen saturation in an ischemia-reperfusion model in humans" @default.
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- W3133056128 doi "https://doi.org/10.1364/boe.418397" @default.
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