FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3133247890> ?p ?o ?g. }

• W3133247890 abstract "Caenorhabditis elegans is an instrumental research model used to advance our knowledge in areas including development, metabolism, and aging. However, research on metabolism and/or other measures of health/aging are confounded by the nematode's food source in the lab, live E. coli bacteria. Commonly used treatments, including ultraviolet irradiation and antibiotics, are successful in preventing bacterial replication, but the bacteria can remain metabolically active. The purpose of this study is to develop a metabolically inactive food source for the worms that will allow us to minimize the confounding effects of bacterial metabolism on worm metabolism and aging. Our strategy is to use a paraformaldehyde (PFA) treated E. coli food source and to determine its effects on worm health, metabolism and longevity. We initially determine the lowest possible concentrations of PFA necessary to rapidly and reproducibly kill bacteria. We then measure various aspects of worm behavior, healthspan and longevity, including growth rate, food attraction, brood size, lifespan and metabolic assessments, such as oxygen consumption and metabolomics. Our resulting data show that worms eat and grow well on these bacteria and support the use of 0.5% PFA-killed bacteria as a nematode food source for metabolic, drug, and longevity experiments." @default.
• W3133247890 created "2021-03-01" @default.
• W3133247890 creator A5008234108 @default.
• W3133247890 creator A5045080688 @default.
• W3133247890 creator A5055718290 @default.
• W3133247890 creator A5057415573 @default.
• W3133247890 creator A5066764553 @default.
• W3133247890 creator A5068771233 @default.
• W3133247890 creator A5076972496 @default.
• W3133247890 creator A5084035153 @default.
• W3133247890 creator A5091035032 @default.
• W3133247890 creator A5091065710 @default.
• W3133247890 date "2021-02-26" @default.
• W3133247890 modified "2023-10-16" @default.
• W3133247890 title "An alternative food source for metabolism and longevity studies in Caenorhabditis elegans" @default.
• W3133247890 cites W1518907982 @default.
• W3133247890 cites W1539153803 @default.
• W3133247890 cites W1811526771 @default.
• W3133247890 cites W1826402150 @default.
• W3133247890 cites W1964010911 @default.
• W3133247890 cites W1967695632 @default.
• W3133247890 cites W1970349598 @default.
• W3133247890 cites W1993519767 @default.
• W3133247890 cites W2003563200 @default.
• W3133247890 cites W2008371754 @default.
• W3133247890 cites W2044848395 @default.
• W3133247890 cites W2051033597 @default.
• W3133247890 cites W2064144155 @default.
• W3133247890 cites W2070567074 @default.
• W3133247890 cites W2099540110 @default.
• W3133247890 cites W2115010963 @default.
• W3133247890 cites W2119629514 @default.
• W3133247890 cites W2129796656 @default.
• W3133247890 cites W2133130607 @default.
• W3133247890 cites W2136351174 @default.
• W3133247890 cites W2151034892 @default.
• W3133247890 cites W2152839556 @default.
• W3133247890 cites W2170979056 @default.
• W3133247890 cites W2265714433 @default.
• W3133247890 cites W2412259962 @default.
• W3133247890 cites W2515386838 @default.
• W3133247890 cites W2620966823 @default.
• W3133247890 cites W2753107316 @default.
• W3133247890 cites W4300009529 @default.
• W3133247890 cites W978867059 @default.
• W3133247890 doi "https://doi.org/10.1038/s42003-021-01764-4" @default.
• W3133247890 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7910432" @default.
• W3133247890 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33637830" @default.
• W3133247890 hasPublicationYear "2021" @default.
• W3133247890 type Work @default.
• W3133247890 sameAs 3133247890 @default.
• W3133247890 citedByCount "22" @default.
• W3133247890 countsByYear W31332478902021 @default.
• W3133247890 countsByYear W31332478902022 @default.
• W3133247890 countsByYear W31332478902023 @default.
• W3133247890 crossrefType "journal-article" @default.
• W3133247890 hasAuthorship W3133247890A5008234108 @default.
• W3133247890 hasAuthorship W3133247890A5045080688 @default.
• W3133247890 hasAuthorship W3133247890A5055718290 @default.
• W3133247890 hasAuthorship W3133247890A5057415573 @default.
• W3133247890 hasAuthorship W3133247890A5066764553 @default.
• W3133247890 hasAuthorship W3133247890A5068771233 @default.
• W3133247890 hasAuthorship W3133247890A5076972496 @default.
• W3133247890 hasAuthorship W3133247890A5084035153 @default.
• W3133247890 hasAuthorship W3133247890A5091035032 @default.
• W3133247890 hasAuthorship W3133247890A5091065710 @default.
• W3133247890 hasBestOaLocation W31332478901 @default.
• W3133247890 hasConcept C104317684 @default.
• W3133247890 hasConcept C2776759703 @default.
• W3133247890 hasConcept C2778944004 @default.
• W3133247890 hasConcept C31903555 @default.
• W3133247890 hasConcept C523546767 @default.
• W3133247890 hasConcept C54355233 @default.
• W3133247890 hasConcept C55493867 @default.
• W3133247890 hasConcept C86803240 @default.
• W3133247890 hasConcept C89423630 @default.
• W3133247890 hasConceptScore W3133247890C104317684 @default.
• W3133247890 hasConceptScore W3133247890C2776759703 @default.
• W3133247890 hasConceptScore W3133247890C2778944004 @default.
• W3133247890 hasConceptScore W3133247890C31903555 @default.
• W3133247890 hasConceptScore W3133247890C523546767 @default.
• W3133247890 hasConceptScore W3133247890C54355233 @default.
• W3133247890 hasConceptScore W3133247890C55493867 @default.
• W3133247890 hasConceptScore W3133247890C86803240 @default.
• W3133247890 hasConceptScore W3133247890C89423630 @default.
• W3133247890 hasIssue "1" @default.
• W3133247890 hasLocation W31332478901 @default.
• W3133247890 hasLocation W31332478902 @default.
• W3133247890 hasLocation W31332478903 @default.
• W3133247890 hasOpenAccess W3133247890 @default.
• W3133247890 hasPrimaryLocation W31332478901 @default.
• W3133247890 hasRelatedWork W1841816992 @default.
• W3133247890 hasRelatedWork W2016097750 @default.
• W3133247890 hasRelatedWork W2089106442 @default.
• W3133247890 hasRelatedWork W2097265502 @default.
• W3133247890 hasRelatedWork W2099286775 @default.
• W3133247890 hasRelatedWork W2130801271 @default.
• W3133247890 hasRelatedWork W2179622651 @default.
• W3133247890 hasRelatedWork W2329720879 @default.
• W3133247890 hasRelatedWork W2999594376 @default.

• next