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- W3133274311 abstract "Abstract To evaluate architectural deformities of the liver under congestive conditions, shear wave elastography (SWE) was measured in the supine (Sp) and left decubitus (Ld) positions in 298 subjects. The inferior vena cava (IVC) diameter was significantly reduced at Ld in subjects with higher Ld-SWE than Sp-SWE but not in those with lower Ld-SWE. In 81 subjects, Sp-SWE was increased or decreased in Ld beyond the magnitude of robust coefficient of variation. Among these subjects, all 37 with normal Sp-SWE had higher Ld-SWE than Sp-SWE (NH), whereas in 44 residual subjects with abnormal Sp-SWE Ld-SWE was higher in 27 subjects (HH) and lower in 17 subjects (HS) than Sp-SWE. Sp-SWE was significantly correlated with the difference between Sp-SWE and Ld-SWE only in HS. When HH and HS were examined for each lobe, Fibrosis-4 or platelet counts were significantly higher only for HS versus NH. The paradoxical increase/decrease of liver stiffness/IVC diameter in Ld indicates the pressure threshold between the hepatic veins and IVC. Gravity alters the hepatic architecture during body postural changes, causing outflow blockage in hepatic veins. A rigid liver is resistant to structural deformation. Stiff-liver softening in Ld suggests fibrous liver." @default.
- W3133274311 created "2021-03-01" @default.
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- W3133274311 date "2021-02-12" @default.
- W3133274311 modified "2023-10-16" @default.
- W3133274311 title "Detection of Fibrous Liver Under Congestion by a Gravity-assisted Evaluation of Liver Stiffness" @default.
- W3133274311 doi "https://doi.org/10.21203/rs.3.rs-187819/v1" @default.
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