FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3133313394> ?p ?o ?g. }

• W3133313394 endingPage "104262" @default.
• W3133313394 startingPage "104262" @default.
• W3133313394 abstract "The pathogenic mutation p.Arg14del in the gene encoding Phospholamban (PLN) is known to cause cardiomyopathy and leads to increased risk of sudden cardiac death. Automatic tools might improve the detection of patients with this rare disease. Deep learning is currently the state-of-the-art in signal processing but requires large amounts of data to train the algorithms. In situations with relatively small amounts of data, like PLN, transfer learning may improve accuracy. We propose an ECG-based detection of the PLN mutation using transfer learning from a model originally trained for sex identification. The sex identification model was trained with 256,278 ECGs and subsequently finetuned for PLN detection (155 ECGs of patients with PLN) with two control groups: a balanced age/sex matched group and a randomly selected imbalanced population. The data was split in 10 folds and 20% of the training data was used for validation and early stopping. The models were evaluated with the area under the receiver operating characteristic curve (AUROC) of the testing data. We used gradient activation for explanation of the prediction models. The models trained with transfer learning outperformed the models trained from scratch for both the balanced (AUROC 0.87 vs AUROC 0.71) and imbalanced (AUROC 0.0.90 vs AUROC 0.65) population. The proposed approach was able to improve the accuracy of a rare disease detection model by transfer learning information from a non-manual annotated and abundant label with only limited data available." @default.
• W3133313394 created "2021-03-01" @default.
• W3133313394 creator A5002151074 @default.
• W3133313394 creator A5012416515 @default.
• W3133313394 creator A5013611389 @default.
• W3133313394 creator A5020918126 @default.
• W3133313394 creator A5039557474 @default.
• W3133313394 creator A5045083789 @default.
• W3133313394 creator A5047299708 @default.
• W3133313394 creator A5050776175 @default.
• W3133313394 creator A5061943173 @default.
• W3133313394 date "2021-04-01" @default.
• W3133313394 modified "2023-10-11" @default.
• W3133313394 title "Improving electrocardiogram-based detection of rare genetic heart disease using transfer learning: An application to phospholamban p.Arg14del mutation carriers" @default.
• W3133313394 cites W1966716734 @default.
• W3133313394 cites W1973604073 @default.
• W3133313394 cites W2015195838 @default.
• W3133313394 cites W2097680164 @default.
• W3133313394 cites W2139331439 @default.
• W3133313394 cites W2146665756 @default.
• W3133313394 cites W2154039449 @default.
• W3133313394 cites W2170124209 @default.
• W3133313394 cites W2620656322 @default.
• W3133313394 cites W2759456125 @default.
• W3133313394 cites W2771170013 @default.
• W3133313394 cites W2784316640 @default.
• W3133313394 cites W2903973636 @default.
• W3133313394 cites W2904739952 @default.
• W3133313394 cites W2916393318 @default.
• W3133313394 cites W2944140727 @default.
• W3133313394 cites W2970154784 @default.
• W3133313394 cites W3000302224 @default.
• W3133313394 cites W3081864884 @default.
• W3133313394 cites W3084352865 @default.
• W3133313394 cites W3086094900 @default.
• W3133313394 cites W3099085560 @default.
• W3133313394 doi "https://doi.org/10.1016/j.compbiomed.2021.104262" @default.
• W3133313394 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33607378" @default.
• W3133313394 hasPublicationYear "2021" @default.
• W3133313394 type Work @default.
• W3133313394 sameAs 3133313394 @default.
• W3133313394 citedByCount "22" @default.
• W3133313394 countsByYear W31333133942021 @default.
• W3133313394 countsByYear W31333133942022 @default.
• W3133313394 countsByYear W31333133942023 @default.
• W3133313394 crossrefType "journal-article" @default.
• W3133313394 hasAuthorship W3133313394A5002151074 @default.
• W3133313394 hasAuthorship W3133313394A5012416515 @default.
• W3133313394 hasAuthorship W3133313394A5013611389 @default.
• W3133313394 hasAuthorship W3133313394A5020918126 @default.
• W3133313394 hasAuthorship W3133313394A5039557474 @default.
• W3133313394 hasAuthorship W3133313394A5045083789 @default.
• W3133313394 hasAuthorship W3133313394A5047299708 @default.
• W3133313394 hasAuthorship W3133313394A5050776175 @default.
• W3133313394 hasAuthorship W3133313394A5061943173 @default.
• W3133313394 hasBestOaLocation W31333133941 @default.
• W3133313394 hasConcept C104317684 @default.
• W3133313394 hasConcept C108583219 @default.
• W3133313394 hasConcept C119857082 @default.
• W3133313394 hasConcept C126322002 @default.
• W3133313394 hasConcept C150899416 @default.
• W3133313394 hasConcept C154945302 @default.
• W3133313394 hasConcept C17137333 @default.
• W3133313394 hasConcept C2778198053 @default.
• W3133313394 hasConcept C2908647359 @default.
• W3133313394 hasConcept C41008148 @default.
• W3133313394 hasConcept C501734568 @default.
• W3133313394 hasConcept C55493867 @default.
• W3133313394 hasConcept C58471807 @default.
• W3133313394 hasConcept C71924100 @default.
• W3133313394 hasConcept C86803240 @default.
• W3133313394 hasConcept C99454951 @default.
• W3133313394 hasConceptScore W3133313394C104317684 @default.
• W3133313394 hasConceptScore W3133313394C108583219 @default.
• W3133313394 hasConceptScore W3133313394C119857082 @default.
• W3133313394 hasConceptScore W3133313394C126322002 @default.
• W3133313394 hasConceptScore W3133313394C150899416 @default.
• W3133313394 hasConceptScore W3133313394C154945302 @default.
• W3133313394 hasConceptScore W3133313394C17137333 @default.
• W3133313394 hasConceptScore W3133313394C2778198053 @default.
• W3133313394 hasConceptScore W3133313394C2908647359 @default.
• W3133313394 hasConceptScore W3133313394C41008148 @default.
• W3133313394 hasConceptScore W3133313394C501734568 @default.
• W3133313394 hasConceptScore W3133313394C55493867 @default.
• W3133313394 hasConceptScore W3133313394C58471807 @default.
• W3133313394 hasConceptScore W3133313394C71924100 @default.
• W3133313394 hasConceptScore W3133313394C86803240 @default.
• W3133313394 hasConceptScore W3133313394C99454951 @default.
• W3133313394 hasFunder F4320313144 @default.
• W3133313394 hasFunder F4320321008 @default.
• W3133313394 hasLocation W31333133941 @default.
• W3133313394 hasOpenAccess W3133313394 @default.
• W3133313394 hasPrimaryLocation W31333133941 @default.
• W3133313394 hasRelatedWork W2951211570 @default.
• W3133313394 hasRelatedWork W3023427754 @default.
• W3133313394 hasRelatedWork W3131673289 @default.
• W3133313394 hasRelatedWork W3167935049 @default.
• W3133313394 hasRelatedWork W3178390372 @default.

• next