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- W3133430735 endingPage "429" @default.
- W3133430735 startingPage "414" @default.
- W3133430735 abstract "Protozoan parasites acquire essential ions, nutrients, and other solutes from their insect and vertebrate hosts by transmembrane uptake. For intracellular stages, these solutes must cross additional membranous barriers. At each step, ion channels and transporters mediate not only this uptake but also the removal of waste products. These transport proteins are best isolated and studied with patch-clamp, but these methods remain accessible to only a few parasitologists due to specialized instrumentation and the required training in both theory and practice. Here, we provide an overview of patch-clamp, describing the advantages and limitations of the technology and highlighting issues that may lead to incorrect conclusions. We aim to help non-experts understand and critically assess patch-clamp data in basic research studies." @default.
- W3133430735 created "2021-03-01" @default.
- W3133430735 creator A5025683949 @default.
- W3133430735 creator A5046001598 @default.
- W3133430735 creator A5059162990 @default.
- W3133430735 date "2021-05-01" @default.
- W3133430735 modified "2023-10-13" @default.
- W3133430735 title "Promises and Pitfalls of Parasite Patch-clamp" @default.
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