Matches in SemOpenAlex for { <https://semopenalex.org/work/W3133592010> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W3133592010 endingPage "153542" @default.
- W3133592010 startingPage "153542" @default.
- W3133592010 abstract "Paridis Rhizoma (PR) is a famous traditional herbal medicine. Apart from two officially recorded species, viz. Paris polyphylla Smith var. yunnanensis (Franch.) Hand. - Mazz. (PPY) and P. polyphylla Smith var. chinensis (Franch.) Hara (PPC), there are still many other species used as folk medicine. It is necessary to understand the metabolic differences among Paris species. To establish a strategy that can discover species-specific steroidal saponin markers to distinguish closely-related Paris herbs for quality and safety control. A new strategy of molecular-networking-guided discovery of species-specific markers was proposed. Firstly, the ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS) was applied to obtain the MS and MS/MS data of all samples. Then, molecular networking (MN) was created using MS/MS data to prescreen the steroidal saponins for subsequent analysis. Next, the principal component analysis (PCA) and orthogonal partial least square discriminant analysis (OPLS-DA) models were established to discover potential markers. Finally, the verification, identification and distribution of chemical markers were performed. A total of 126 steroidal saponins were screened out from five species using MN. Five species were classified successfully by OPLS-DA model, and 18 species-specific markers were discovered combining the variable importance in the projection (VIP) value, P value (one-way ANOVA) and their relative abundance. These markers could predict the species of Paris herbs correctly. These results revealed that this new strategy could be an efficient way for chemical discrimination of medicinal herbs with close genetic relationship." @default.
- W3133592010 created "2021-03-15" @default.
- W3133592010 creator A5018221142 @default.
- W3133592010 creator A5025834518 @default.
- W3133592010 creator A5032594322 @default.
- W3133592010 creator A5054711300 @default.
- W3133592010 creator A5054775586 @default.
- W3133592010 creator A5080932283 @default.
- W3133592010 creator A5086241180 @default.
- W3133592010 date "2021-05-01" @default.
- W3133592010 modified "2023-10-14" @default.
- W3133592010 title "Molecular-networking-guided discovery of species-specific markers for discriminating five medicinal Paris herbs" @default.
- W3133592010 cites W2030592683 @default.
- W3133592010 cites W2227911882 @default.
- W3133592010 cites W2283606770 @default.
- W3133592010 cites W2413775558 @default.
- W3133592010 cites W2555163954 @default.
- W3133592010 cites W2595592100 @default.
- W3133592010 cites W2611965203 @default.
- W3133592010 cites W2621418128 @default.
- W3133592010 cites W2742146026 @default.
- W3133592010 cites W2790631918 @default.
- W3133592010 cites W2791685183 @default.
- W3133592010 cites W2795445977 @default.
- W3133592010 cites W2888598069 @default.
- W3133592010 cites W2901202444 @default.
- W3133592010 cites W2914903199 @default.
- W3133592010 cites W2920281801 @default.
- W3133592010 cites W2921197223 @default.
- W3133592010 cites W2939988707 @default.
- W3133592010 cites W2983439236 @default.
- W3133592010 cites W2996940961 @default.
- W3133592010 cites W3017090987 @default.
- W3133592010 cites W3024889274 @default.
- W3133592010 cites W3040063233 @default.
- W3133592010 doi "https://doi.org/10.1016/j.phymed.2021.153542" @default.
- W3133592010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33799225" @default.
- W3133592010 hasPublicationYear "2021" @default.
- W3133592010 type Work @default.
- W3133592010 sameAs 3133592010 @default.
- W3133592010 citedByCount "11" @default.
- W3133592010 countsByYear W31335920102021 @default.
- W3133592010 countsByYear W31335920102022 @default.
- W3133592010 countsByYear W31335920102023 @default.
- W3133592010 crossrefType "journal-article" @default.
- W3133592010 hasAuthorship W3133592010A5018221142 @default.
- W3133592010 hasAuthorship W3133592010A5025834518 @default.
- W3133592010 hasAuthorship W3133592010A5032594322 @default.
- W3133592010 hasAuthorship W3133592010A5054711300 @default.
- W3133592010 hasAuthorship W3133592010A5054775586 @default.
- W3133592010 hasAuthorship W3133592010A5080932283 @default.
- W3133592010 hasAuthorship W3133592010A5086241180 @default.
- W3133592010 hasConcept C154945302 @default.
- W3133592010 hasConcept C185592680 @default.
- W3133592010 hasConcept C21565614 @default.
- W3133592010 hasConcept C27438332 @default.
- W3133592010 hasConcept C2991655182 @default.
- W3133592010 hasConcept C2994380890 @default.
- W3133592010 hasConcept C41008148 @default.
- W3133592010 hasConcept C43617362 @default.
- W3133592010 hasConcept C556039675 @default.
- W3133592010 hasConcept C60644358 @default.
- W3133592010 hasConcept C70721500 @default.
- W3133592010 hasConcept C71924100 @default.
- W3133592010 hasConcept C86803240 @default.
- W3133592010 hasConceptScore W3133592010C154945302 @default.
- W3133592010 hasConceptScore W3133592010C185592680 @default.
- W3133592010 hasConceptScore W3133592010C21565614 @default.
- W3133592010 hasConceptScore W3133592010C27438332 @default.
- W3133592010 hasConceptScore W3133592010C2991655182 @default.
- W3133592010 hasConceptScore W3133592010C2994380890 @default.
- W3133592010 hasConceptScore W3133592010C41008148 @default.
- W3133592010 hasConceptScore W3133592010C43617362 @default.
- W3133592010 hasConceptScore W3133592010C556039675 @default.
- W3133592010 hasConceptScore W3133592010C60644358 @default.
- W3133592010 hasConceptScore W3133592010C70721500 @default.
- W3133592010 hasConceptScore W3133592010C71924100 @default.
- W3133592010 hasConceptScore W3133592010C86803240 @default.
- W3133592010 hasFunder F4320321540 @default.
- W3133592010 hasLocation W31335920101 @default.
- W3133592010 hasOpenAccess W3133592010 @default.
- W3133592010 hasPrimaryLocation W31335920101 @default.
- W3133592010 hasRelatedWork W1916466758 @default.
- W3133592010 hasRelatedWork W2041461681 @default.
- W3133592010 hasRelatedWork W2137270828 @default.
- W3133592010 hasRelatedWork W2333363243 @default.
- W3133592010 hasRelatedWork W2383408506 @default.
- W3133592010 hasRelatedWork W2469500194 @default.
- W3133592010 hasRelatedWork W2799971091 @default.
- W3133592010 hasRelatedWork W4221102017 @default.
- W3133592010 hasRelatedWork W42525420 @default.
- W3133592010 hasRelatedWork W4283390424 @default.
- W3133592010 hasVolume "85" @default.
- W3133592010 isParatext "false" @default.
- W3133592010 isRetracted "false" @default.
- W3133592010 magId "3133592010" @default.
- W3133592010 workType "article" @default.