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• W3133640765 abstract "To identify factors associated with development of symptomatic infection in infants colonized with methicillin-resistant Staphylococcus aureus (MRSA) in the Neonatal Intensive Care Unit (NICU). This case-control study was performed at St. Louis Children’s Hospital NICU from 2009 to 2019. The MRSA-colonized infants who developed symptomatic MRSA infection (cases) were matched 1:3 with MRSA-colonized infants who did not develop infection (controls). Demographics and characteristics of NICU course were compared between groups. Longitudinal information from subsequent hospitalizations was also obtained. Forty-two infected cases were compared with 126 colonized-only controls. Cases became colonized earlier in their NICU stay, were less likely to have received mupirocin for decolonization, and had a longer course of mechanical ventilation than controls. Longitudinally, cases had a more protracted NICU course and were more likely to require hospital readmission. Progression from MRSA colonization to symptomatic infection is associated with increased morbidity and may be mitigated through decolonization." @default.
• W3133640765 created "2021-03-15" @default.
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• W3133640765 date "2021-03-01" @default.
• W3133640765 modified "2023-10-16" @default.
• W3133640765 title "Factors associated with progression to infection in methicillin-resistant Staphylococcus aureus-colonized, critically ill neonates" @default.
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• W3133640765 doi "https://doi.org/10.1038/s41372-021-00944-8" @default.
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