FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3133655574> ?p ?o ?g. }

• W3133655574 endingPage "12" @default.
• W3133655574 startingPage "12" @default.
• W3133655574 abstract "Purpose: We used optical coherence tomography angiography to test the hypothesis that more complex, multilayered choroidal neovascular (CNV) membranes in AMD are associated with worse flow deficits (FD) in the choriocapillaris. Methods: Retrospective, cross-sectional study including 29 eyes of 29 subjects with neovascular AMD. En face choriocapillaris images were compensated for signal attenuation using the structural OCT slab and signal normalization based on a cohort of healthy subjects. We binarized the choriocapillaris using both local Phansalkar and global MinError(I) methods and quantified FD count, FD density, and mean FD size in the entire area outside the CNV, in the 200-µm annulus surrounding the CNV, and in the area outside the annulus. We used projection-resolved optical coherence tomography angiography to quantify CNV complexity, including highest CNV flow height, number of flow layers, and flow layer thickness. We explored the relationship between CNV complexity and choriocapillaris FD using Spearman correlations. Results: The highest CNV flow signal significantly correlated with lower FD count (P < 0.01), higher FD density (P < 0.05), and higher mean FD size (P < 0.05) in the area outside the annulus and the entire area outside the CNV using both Phansalkar and MinError(I). Within the annulus, CNV complexity was not consistently correlated with choriocapillaris defects. Conclusions: CNV vascular complexity is correlated with choriocapillaris FD outside the CNV area, providing evidence for the importance of choriocapillaris dysfunction in neovascular AMD, as well as the potential role of choroidal ischemia in the pathogenesis of complex CNV membranes." @default.
• W3133655574 created "2021-03-15" @default.
• W3133655574 creator A5042290766 @default.
• W3133655574 creator A5056615212 @default.
• W3133655574 creator A5079152380 @default.
• W3133655574 date "2021-03-09" @default.
• W3133655574 modified "2023-10-16" @default.
• W3133655574 title "Exploring the Relationship Between Multilayered Choroidal Neovascularization and Choriocapillaris Flow Deficits in AMD" @default.
• W3133655574 cites W1976433015 @default.
• W3133655574 cites W1984153831 @default.
• W3133655574 cites W1992868980 @default.
• W3133655574 cites W1994734383 @default.
• W3133655574 cites W1996821302 @default.
• W3133655574 cites W2012322597 @default.
• W3133655574 cites W2014210274 @default.
• W3133655574 cites W2017115804 @default.
• W3133655574 cites W2027091505 @default.
• W3133655574 cites W2051842051 @default.
• W3133655574 cites W2061273505 @default.
• W3133655574 cites W2071516577 @default.
• W3133655574 cites W2085712747 @default.
• W3133655574 cites W2094739999 @default.
• W3133655574 cites W2099838434 @default.
• W3133655574 cites W2114112168 @default.
• W3133655574 cites W2124415048 @default.
• W3133655574 cites W2135957358 @default.
• W3133655574 cites W2139769620 @default.
• W3133655574 cites W2143408104 @default.
• W3133655574 cites W2155236757 @default.
• W3133655574 cites W2163069245 @default.
• W3133655574 cites W2167279371 @default.
• W3133655574 cites W2252774054 @default.
• W3133655574 cites W2333569680 @default.
• W3133655574 cites W2406931263 @default.
• W3133655574 cites W2522606404 @default.
• W3133655574 cites W2527824850 @default.
• W3133655574 cites W2547788753 @default.
• W3133655574 cites W2749678738 @default.
• W3133655574 cites W2765604220 @default.
• W3133655574 cites W2766557075 @default.
• W3133655574 cites W2784283772 @default.
• W3133655574 cites W2790605553 @default.
• W3133655574 cites W2795575482 @default.
• W3133655574 cites W2885530818 @default.
• W3133655574 cites W2894529439 @default.
• W3133655574 cites W2899072153 @default.
• W3133655574 cites W2901004898 @default.
• W3133655574 cites W2904608183 @default.
• W3133655574 cites W2920807903 @default.
• W3133655574 cites W2936953565 @default.
• W3133655574 cites W2958447652 @default.
• W3133655574 cites W2964546533 @default.
• W3133655574 cites W2969042142 @default.
• W3133655574 cites W3004143075 @default.
• W3133655574 cites W3005953471 @default.
• W3133655574 cites W3027928437 @default.
• W3133655574 cites W3041879893 @default.
• W3133655574 cites W3083111074 @default.
• W3133655574 cites W3084131940 @default.
• W3133655574 cites W4233657213 @default.
• W3133655574 cites W4237713631 @default.
• W3133655574 doi "https://doi.org/10.1167/iovs.62.3.12" @default.
• W3133655574 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7960838" @default.
• W3133655574 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33687474" @default.
• W3133655574 hasPublicationYear "2021" @default.
• W3133655574 type Work @default.
• W3133655574 sameAs 3133655574 @default.
• W3133655574 citedByCount "7" @default.
• W3133655574 countsByYear W31336555742022 @default.
• W3133655574 countsByYear W31336555742023 @default.
• W3133655574 crossrefType "journal-article" @default.
• W3133655574 hasAuthorship W3133655574A5042290766 @default.
• W3133655574 hasAuthorship W3133655574A5056615212 @default.
• W3133655574 hasAuthorship W3133655574A5079152380 @default.
• W3133655574 hasBestOaLocation W31336555741 @default.
• W3133655574 hasConcept C118487528 @default.
• W3133655574 hasConcept C2776403814 @default.
• W3133655574 hasConcept C2778818243 @default.
• W3133655574 hasConcept C2781359195 @default.
• W3133655574 hasConcept C2985858981 @default.
• W3133655574 hasConcept C71924100 @default.
• W3133655574 hasConceptScore W3133655574C118487528 @default.
• W3133655574 hasConceptScore W3133655574C2776403814 @default.
• W3133655574 hasConceptScore W3133655574C2778818243 @default.
• W3133655574 hasConceptScore W3133655574C2781359195 @default.
• W3133655574 hasConceptScore W3133655574C2985858981 @default.
• W3133655574 hasConceptScore W3133655574C71924100 @default.
• W3133655574 hasIssue "3" @default.
• W3133655574 hasLocation W31336555741 @default.
• W3133655574 hasLocation W31336555742 @default.
• W3133655574 hasOpenAccess W3133655574 @default.
• W3133655574 hasPrimaryLocation W31336555741 @default.
• W3133655574 hasRelatedWork W1171819408 @default.
• W3133655574 hasRelatedWork W2006876183 @default.
• W3133655574 hasRelatedWork W2616362931 @default.
• W3133655574 hasRelatedWork W2908153085 @default.
• W3133655574 hasRelatedWork W2982685807 @default.
• W3133655574 hasRelatedWork W2994351038 @default.

• next