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- W3133728352 abstract "Low molecular weight heparins, in particular enoxaparin, have a wide range of applications, including prevention and treatment of deep vein thrombosis. The most common adverse effects of these drugs are bleeding and thrombocytopenia, but a clinician should be aware of another less common but not less important adverse effect such as an elevated transaminase level. In 2019, we observed two cases of enoxaparin-induced hepatotoxicity. In the first one, enoxaparin 0.4 ml subcutaneously twice a day was prescribed to a 40-year-old woman as a bridge therapy to discontinue warfarin before elective surgery. In the second case, a 27-year-old man received enoxaparin 0.4 ml subcutaneously twice a day for the prevention of deep vein thrombosis. The elevation of transaminase level for more than 3 times above the norm was noted in both patients which required discontinuation of the drug." @default.
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- W3133728352 date "2021-03-06" @default.
- W3133728352 modified "2023-10-16" @default.
- W3133728352 title "Enoxaparin-induced hepatotoxicity: clinical cases and literature review" @default.
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- W3133728352 doi "https://doi.org/10.21292/2078-5658-2021-18-1-84-92" @default.
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