Matches in SemOpenAlex for { <https://semopenalex.org/work/W3133730607> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W3133730607 abstract "Abstract Aims The aim of this study was to make a quantitative comparison of plan quality between MLC-based EDGE system and the cone-based CyberKnife system in stereotactic body radiation therapy (SBRT) for patients with localized prostate cancer. Materials and methods Ten patients with prostate volumes ranging from 34.65 to 82.16 cc were used for prostate SBRT. Treatment plans were created for both EDGE and CyberKnife G4 systems using the same dose-volume constraints. Dosimetric indices including Planning Tumor Volume (PTV) coverage, conformity index ( CI ), new conformity index ( nCI ), homogeneity index ( HI ), gradient index ( GI ) were applied for target, while the sparing of critical organs, including bladder, rectum, femoral heads, urethra, penile bulk and normal tissue outside PTV), were evaluated interms of various dose-volume metrics and integral dose (ID). Meanwhile, the required delivery time and number of monitor units (MUs) during irradiation were measured to estimate the treatment efficiency. The radiobiological indices such as equivalent uniform dose ( EUD ), tumor control probability ( TCP ) and the normal tissue complication probability ( NTCP ) were also analyzed. Results All dose constraints were achieved by both systems. It showed that the DEGE plans results were closest to the CK plans results in terms of PTV coverage, HI and GI . For EDGE, more conformal dose distribution in the target as well as reduced exposure of critical organs were obtained together with reduction of 91% delivery time and 72% monitor units. EDGE plans also got lower EUD for bladder, rectum, urethra and penile bulk, which associated with reduction of NTCPs. However, higher values of EUD and TCP for tumor were obtained with CK plans. Conclusions Our study indicated that both systems were capable of producing almost equivalent plan quality and can meet clinical requirements. CyberKnife G4 system has higher target dose while EDGE system has more advantages based on the considerations of normal tissue sparing and delivery efficiency. With abundant clinical experience, CK provides accurate SBRT treatment with high quality. EDGE system also can be considered to be an option for SBRT treatment for localized prostate cancer treatment." @default.
- W3133730607 created "2021-03-15" @default.
- W3133730607 creator A5003693436 @default.
- W3133730607 creator A5024596713 @default.
- W3133730607 creator A5025992036 @default.
- W3133730607 creator A5026308498 @default.
- W3133730607 creator A5039287818 @default.
- W3133730607 creator A5040148684 @default.
- W3133730607 creator A5043673328 @default.
- W3133730607 creator A5047641031 @default.
- W3133730607 creator A5082255460 @default.
- W3133730607 creator A5084550804 @default.
- W3133730607 creator A5085083598 @default.
- W3133730607 date "2021-02-22" @default.
- W3133730607 modified "2023-09-27" @default.
- W3133730607 title "Dosimetric and biological comparison of treatment plans between LINAC and robot systems in stereotactic body radiation therapy for localized prostate cancer" @default.
- W3133730607 doi "https://doi.org/10.21203/rs.3.rs-148017/v1" @default.
- W3133730607 hasPublicationYear "2021" @default.
- W3133730607 type Work @default.
- W3133730607 sameAs 3133730607 @default.
- W3133730607 citedByCount "0" @default.
- W3133730607 crossrefType "posted-content" @default.
- W3133730607 hasAuthorship W3133730607A5003693436 @default.
- W3133730607 hasAuthorship W3133730607A5024596713 @default.
- W3133730607 hasAuthorship W3133730607A5025992036 @default.
- W3133730607 hasAuthorship W3133730607A5026308498 @default.
- W3133730607 hasAuthorship W3133730607A5039287818 @default.
- W3133730607 hasAuthorship W3133730607A5040148684 @default.
- W3133730607 hasAuthorship W3133730607A5043673328 @default.
- W3133730607 hasAuthorship W3133730607A5047641031 @default.
- W3133730607 hasAuthorship W3133730607A5082255460 @default.
- W3133730607 hasAuthorship W3133730607A5084550804 @default.
- W3133730607 hasAuthorship W3133730607A5085083598 @default.
- W3133730607 hasBestOaLocation W31337306071 @default.
- W3133730607 hasConcept C120665830 @default.
- W3133730607 hasConcept C121332964 @default.
- W3133730607 hasConcept C121608353 @default.
- W3133730607 hasConcept C126322002 @default.
- W3133730607 hasConcept C126838900 @default.
- W3133730607 hasConcept C141071460 @default.
- W3133730607 hasConcept C168834538 @default.
- W3133730607 hasConcept C180048950 @default.
- W3133730607 hasConcept C201645570 @default.
- W3133730607 hasConcept C2776235491 @default.
- W3133730607 hasConcept C2776651944 @default.
- W3133730607 hasConcept C2780192828 @default.
- W3133730607 hasConcept C2780271382 @default.
- W3133730607 hasConcept C2780387249 @default.
- W3133730607 hasConcept C2781074409 @default.
- W3133730607 hasConcept C2989005 @default.
- W3133730607 hasConcept C509974204 @default.
- W3133730607 hasConcept C71924100 @default.
- W3133730607 hasConceptScore W3133730607C120665830 @default.
- W3133730607 hasConceptScore W3133730607C121332964 @default.
- W3133730607 hasConceptScore W3133730607C121608353 @default.
- W3133730607 hasConceptScore W3133730607C126322002 @default.
- W3133730607 hasConceptScore W3133730607C126838900 @default.
- W3133730607 hasConceptScore W3133730607C141071460 @default.
- W3133730607 hasConceptScore W3133730607C168834538 @default.
- W3133730607 hasConceptScore W3133730607C180048950 @default.
- W3133730607 hasConceptScore W3133730607C201645570 @default.
- W3133730607 hasConceptScore W3133730607C2776235491 @default.
- W3133730607 hasConceptScore W3133730607C2776651944 @default.
- W3133730607 hasConceptScore W3133730607C2780192828 @default.
- W3133730607 hasConceptScore W3133730607C2780271382 @default.
- W3133730607 hasConceptScore W3133730607C2780387249 @default.
- W3133730607 hasConceptScore W3133730607C2781074409 @default.
- W3133730607 hasConceptScore W3133730607C2989005 @default.
- W3133730607 hasConceptScore W3133730607C509974204 @default.
- W3133730607 hasConceptScore W3133730607C71924100 @default.
- W3133730607 hasLocation W31337306071 @default.
- W3133730607 hasOpenAccess W3133730607 @default.
- W3133730607 hasPrimaryLocation W31337306071 @default.
- W3133730607 hasRelatedWork W1650437112 @default.
- W3133730607 hasRelatedWork W2032769033 @default.
- W3133730607 hasRelatedWork W2128055396 @default.
- W3133730607 hasRelatedWork W2468803844 @default.
- W3133730607 hasRelatedWork W2560837950 @default.
- W3133730607 hasRelatedWork W2888000049 @default.
- W3133730607 hasRelatedWork W2939840252 @default.
- W3133730607 hasRelatedWork W2953263120 @default.
- W3133730607 hasRelatedWork W2955316531 @default.
- W3133730607 hasRelatedWork W4236693431 @default.
- W3133730607 isParatext "false" @default.
- W3133730607 isRetracted "false" @default.
- W3133730607 magId "3133730607" @default.
- W3133730607 workType "article" @default.