Matches in SemOpenAlex for { <https://semopenalex.org/work/W3133733037> ?p ?o ?g. }
- W3133733037 abstract "The hypothalamic–pituitary-gonadal (HPG) axis plays a crucial and integrative role in the mammalian endocrine regulation to maintain homeostasis. The HPG axis is primarily responsible for governing all the hormonal events related to reproductive activity. Endocrine-disrupting chemicals (EDCs) comprise a diverse group of naturally occurring and synthetic compounds that mimic and interfere with the endogenous chemical hormones. Epidemiological investigations have shown increasing evidence of altered development and detrimental effects on reproductive health during the past 50 years associated with endocrine disruptors affecting the HPG axis. The pleiotropic harmful effects of EDCs act through hormone-dependent downstream signaling pathways responsible for gonad development either through direct interaction with steroid hormone receptor or via epigenetic regulation. Hence, this chapter summarizes the biological plausibility of EDCs exposure and elucidates the mechanism of action underlying EDCs affecting the regulatory circuits of the mammalian HPG axis and reproductive function." @default.
- W3133733037 created "2021-03-15" @default.
- W3133733037 creator A5008352148 @default.
- W3133733037 creator A5014832721 @default.
- W3133733037 creator A5048813998 @default.
- W3133733037 creator A5053291773 @default.
- W3133733037 date "2021-12-08" @default.
- W3133733037 modified "2023-09-25" @default.
- W3133733037 title "Effect of Endocrine Disrupting Chemicals on HPG Axis: A Reproductive Endocrine Homeostasis" @default.
- W3133733037 cites W1559989352 @default.
- W3133733037 cites W1932261628 @default.
- W3133733037 cites W1967798994 @default.
- W3133733037 cites W1970223177 @default.
- W3133733037 cites W1972353456 @default.
- W3133733037 cites W1972412158 @default.
- W3133733037 cites W1976629102 @default.
- W3133733037 cites W1981942998 @default.
- W3133733037 cites W1984109965 @default.
- W3133733037 cites W1985934336 @default.
- W3133733037 cites W1988194549 @default.
- W3133733037 cites W1994413221 @default.
- W3133733037 cites W1998352081 @default.
- W3133733037 cites W2000712707 @default.
- W3133733037 cites W2001057309 @default.
- W3133733037 cites W2009040345 @default.
- W3133733037 cites W2015363651 @default.
- W3133733037 cites W2016572372 @default.
- W3133733037 cites W2019699782 @default.
- W3133733037 cites W2023521447 @default.
- W3133733037 cites W2027533003 @default.
- W3133733037 cites W2028071281 @default.
- W3133733037 cites W2032395525 @default.
- W3133733037 cites W2040462127 @default.
- W3133733037 cites W2043155047 @default.
- W3133733037 cites W2048655519 @default.
- W3133733037 cites W2049970571 @default.
- W3133733037 cites W2052704162 @default.
- W3133733037 cites W2057573011 @default.
- W3133733037 cites W2062114651 @default.
- W3133733037 cites W2079258871 @default.
- W3133733037 cites W2080323327 @default.
- W3133733037 cites W2080879610 @default.
- W3133733037 cites W2085223673 @default.
- W3133733037 cites W2090991839 @default.
- W3133733037 cites W2097773172 @default.
- W3133733037 cites W2099760311 @default.
- W3133733037 cites W2100604229 @default.
- W3133733037 cites W2103724391 @default.
- W3133733037 cites W2112484512 @default.
- W3133733037 cites W2118335981 @default.
- W3133733037 cites W2119533233 @default.
- W3133733037 cites W2135182684 @default.
- W3133733037 cites W2146416965 @default.
- W3133733037 cites W2148619299 @default.
- W3133733037 cites W2152874971 @default.
- W3133733037 cites W2157999348 @default.
- W3133733037 cites W2160240007 @default.
- W3133733037 cites W2160337287 @default.
- W3133733037 cites W2160942497 @default.
- W3133733037 cites W2166415807 @default.
- W3133733037 cites W2169173740 @default.
- W3133733037 cites W2171423639 @default.
- W3133733037 cites W2217692751 @default.
- W3133733037 cites W2326379975 @default.
- W3133733037 cites W2338170434 @default.
- W3133733037 cites W2342877679 @default.
- W3133733037 cites W2511238970 @default.
- W3133733037 cites W2511585516 @default.
- W3133733037 cites W2513077713 @default.
- W3133733037 cites W2529344544 @default.
- W3133733037 cites W2593970154 @default.
- W3133733037 cites W2749638421 @default.
- W3133733037 cites W2767671906 @default.
- W3133733037 cites W2767704629 @default.
- W3133733037 cites W2775781603 @default.
- W3133733037 cites W2808244690 @default.
- W3133733037 cites W2897836379 @default.
- W3133733037 cites W2902914441 @default.
- W3133733037 cites W2923451077 @default.
- W3133733037 cites W2992064964 @default.
- W3133733037 cites W3011808565 @default.
- W3133733037 cites W4211011102 @default.
- W3133733037 cites W4242130592 @default.
- W3133733037 cites W4255630062 @default.
- W3133733037 cites W649463998 @default.
- W3133733037 doi "https://doi.org/10.5772/intechopen.96330" @default.
- W3133733037 hasPublicationYear "2021" @default.
- W3133733037 type Work @default.
- W3133733037 sameAs 3133733037 @default.
- W3133733037 citedByCount "4" @default.
- W3133733037 countsByYear W31337330372021 @default.
- W3133733037 countsByYear W31337330372022 @default.
- W3133733037 countsByYear W31337330372023 @default.
- W3133733037 crossrefType "book-chapter" @default.
- W3133733037 hasAuthorship W3133733037A5008352148 @default.
- W3133733037 hasAuthorship W3133733037A5014832721 @default.
- W3133733037 hasAuthorship W3133733037A5048813998 @default.
- W3133733037 hasAuthorship W3133733037A5053291773 @default.
- W3133733037 hasBestOaLocation W31337330371 @default.
- W3133733037 hasConcept C134018914 @default.