FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3133763457> ?p ?o ?g. }

• W3133763457 endingPage "266" @default.
• W3133763457 startingPage "266" @default.
• W3133763457 abstract "Despite their distinct clinical manifestation, frontal fibrosing alopecia (FFA) and lichen planopilaris (LPP) display similar histopathologic features. Aberrant innate immune responses to endogenous or exogenous triggers have been discussed as factors that could drive inflammatory cascades and the collapse of the stem cell niche. In this exploratory study, we investigate the bacterial composition of scalp skin and plucked hair follicles (HF) of patients with FFA, LPP and alopecia areata circumscripta (AAc), as well as healthy individuals, in relation to cellular infiltrates and the expression of defense mediators. The most abundant genus in lesional and non-lesional HFs of LPP and FFA patients was Staphylococcus, while Lawsonella dominated in healthy individuals and in AAc patients. We observed statistically significant differences in the ratio of Firmicutes to Actinobacteria between healthy scalp, lesional, and non-lesional sites of FFA and LPP patients. This marked dysbiosis in FFA and LPP in compartments close to the bulge was associated with increased HβD1 and HβD2 expression along the HFs from lesional sites, while IL-17A was increased in lesional HF from AAc patients. The data encourage further studies on how exogenous factors and molecular interactions across the HF epithelium could contribute to disease onset and propagation." @default.
• W3133763457 created "2021-03-15" @default.
• W3133763457 creator A5015290431 @default.
• W3133763457 creator A5034850910 @default.
• W3133763457 creator A5037986822 @default.
• W3133763457 creator A5058322678 @default.
• W3133763457 creator A5060480453 @default.
• W3133763457 creator A5071414383 @default.
• W3133763457 creator A5072416719 @default.
• W3133763457 creator A5074315116 @default.
• W3133763457 creator A5075931648 @default.
• W3133763457 creator A5077143574 @default.
• W3133763457 creator A5078833348 @default.
• W3133763457 date "2021-03-07" @default.
• W3133763457 modified "2023-10-12" @default.
• W3133763457 title "Dysbiosis and Enhanced Beta-Defensin Production in Hair Follicles of Patients with Lichen Planopilaris and Frontal Fibrosing Alopecia" @default.
• W3133763457 cites W1527622642 @default.
• W3133763457 cites W1529638819 @default.
• W3133763457 cites W1560238970 @default.
• W3133763457 cites W1892796571 @default.
• W3133763457 cites W1977333143 @default.
• W3133763457 cites W1987913143 @default.
• W3133763457 cites W1988279333 @default.
• W3133763457 cites W2002169277 @default.
• W3133763457 cites W2025155127 @default.
• W3133763457 cites W2027544922 @default.
• W3133763457 cites W2034285706 @default.
• W3133763457 cites W2035931280 @default.
• W3133763457 cites W2042957684 @default.
• W3133763457 cites W2047774330 @default.
• W3133763457 cites W2056279562 @default.
• W3133763457 cites W2068984168 @default.
• W3133763457 cites W2079125371 @default.
• W3133763457 cites W2079884351 @default.
• W3133763457 cites W2087731154 @default.
• W3133763457 cites W2091149738 @default.
• W3133763457 cites W2093643274 @default.
• W3133763457 cites W2096991001 @default.
• W3133763457 cites W2099780103 @default.
• W3133763457 cites W2111047538 @default.
• W3133763457 cites W2111808019 @default.
• W3133763457 cites W2154780633 @default.
• W3133763457 cites W2158614332 @default.
• W3133763457 cites W2167579225 @default.
• W3133763457 cites W2291925731 @default.
• W3133763457 cites W2300330529 @default.
• W3133763457 cites W2500807743 @default.
• W3133763457 cites W2597656778 @default.
• W3133763457 cites W2600338286 @default.
• W3133763457 cites W2605650649 @default.
• W3133763457 cites W2751923626 @default.
• W3133763457 cites W2755455242 @default.
• W3133763457 cites W2793857959 @default.
• W3133763457 cites W2796689110 @default.
• W3133763457 cites W2804611869 @default.
• W3133763457 cites W2909668868 @default.
• W3133763457 cites W2913990480 @default.
• W3133763457 cites W2916254331 @default.
• W3133763457 cites W2930037263 @default.
• W3133763457 cites W2936130002 @default.
• W3133763457 cites W2938462422 @default.
• W3133763457 cites W2940378003 @default.
• W3133763457 cites W2952153972 @default.
• W3133763457 cites W2961683485 @default.
• W3133763457 cites W2984177031 @default.
• W3133763457 cites W3011990535 @default.
• W3133763457 cites W3017206483 @default.
• W3133763457 cites W3092150219 @default.
• W3133763457 cites W3093425704 @default.
• W3133763457 cites W3131125758 @default.
• W3133763457 cites W3134211683 @default.
• W3133763457 cites W4236239531 @default.
• W3133763457 cites W977153586 @default.
• W3133763457 doi "https://doi.org/10.3390/biomedicines9030266" @default.
• W3133763457 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7999846" @default.
• W3133763457 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33800045" @default.
• W3133763457 hasPublicationYear "2021" @default.
• W3133763457 type Work @default.
• W3133763457 sameAs 3133763457 @default.
• W3133763457 citedByCount "6" @default.
• W3133763457 countsByYear W31337634572021 @default.
• W3133763457 countsByYear W31337634572022 @default.
• W3133763457 countsByYear W31337634572023 @default.
• W3133763457 crossrefType "journal-article" @default.
• W3133763457 hasAuthorship W3133763457A5015290431 @default.
• W3133763457 hasAuthorship W3133763457A5034850910 @default.
• W3133763457 hasAuthorship W3133763457A5037986822 @default.
• W3133763457 hasAuthorship W3133763457A5058322678 @default.
• W3133763457 hasAuthorship W3133763457A5060480453 @default.
• W3133763457 hasAuthorship W3133763457A5071414383 @default.
• W3133763457 hasAuthorship W3133763457A5072416719 @default.
• W3133763457 hasAuthorship W3133763457A5074315116 @default.
• W3133763457 hasAuthorship W3133763457A5075931648 @default.
• W3133763457 hasAuthorship W3133763457A5077143574 @default.
• W3133763457 hasAuthorship W3133763457A5078833348 @default.
• W3133763457 hasBestOaLocation W31337634571 @default.
• W3133763457 hasConcept C126322002 @default.
• W3133763457 hasConcept C142724271 @default.

• next