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• W3133801006 startingPage "48" @default.
• W3133801006 abstract "The development of drug-resistant tuberculosis (TB) is a major threat worldwide. Based on World Health Organization (WHO) reports, it is estimated that more than 500 000 new cases of drug-resistant TB occur annually. In addition, there are alarming reports of increasing multidrug-resistant TB (MDR-TB) and the emergence of extensively drug-resistant TB (XDR-TB) from different countries of the world. Therefore, new options for TB therapy are required. Bedaquiline (BDQ), a novel anti-TB drug, has significant minimum inhibitory concentrations (MICs) both against drug-susceptible and drug-resistant TB. Moreover, BDQ was recently approved for therapy of MDR-TB. The current narrative review summarises the available data on BDQ resistance, describes its antimicrobial properties, and provides new perspectives on clinical use of this novel anti-TB agent." @default.
• W3133801006 created "2021-03-15" @default.
• W3133801006 creator A5001377133 @default.
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• W3133801006 creator A5046385360 @default.
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• W3133801006 creator A5078191427 @default.
• W3133801006 date "2021-06-01" @default.
• W3133801006 modified "2023-10-11" @default.
• W3133801006 title "Bedaquiline: Current status and future perspectives" @default.
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