FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3133922919> ?p ?o ?g. }

• W3133922919 abstract "Dry eye syndrome (DES), is one of the most common and irritating ocular diseases in humans and animals due to deficits in quantities or/and quality of tear film. In this study, a rat model of experimental DES has been developed using the cholinergic inhibitor, scopolamine hydrobromide (SCOP), at the dose of 25[Formula: see text]mg/rat/day via subcutaneous injection, for a consecutive 21 days without low humidity environment. Clinical ophthalmic evaluations were performed by tear volume assessment using endodontic paper point, slit-lamp biomicroscope, and fluorescein staining at day 0, 7, 14, and 21 post-inductions. The results of ophthalmic examination showed that rats with SCOP treatment reduced about 40% of tear secretion. Half of the SCOP-treated rats exhibited diffuse corneal fluorescein staining involving 80% of the corneal surface, minimal keratoconjunctivitis, roughened corneal surface and thin corneal epithelium under histopathological examination. About 30% of the rats showed variable infiltration of lymphocytes in between the tubular acinar glands. This animal model with significant reduction of tear production and diffuse corneal fluorescein staining in rats could be used for the preclinical assessment of therapeutic interventions." @default.
• W3133922919 created "2021-03-15" @default.
• W3133922919 creator A5015879334 @default.
• W3133922919 creator A5022857093 @default.
• W3133922919 creator A5028107371 @default.
• W3133922919 creator A5062845794 @default.
• W3133922919 creator A5067538672 @default.
• W3133922919 creator A5072171787 @default.
• W3133922919 creator A5091845719 @default.
• W3133922919 date "2020-12-01" @default.
• W3133922919 modified "2023-09-25" @default.
• W3133922919 title "CLINICAL AND HISTOPATHOLOGICAL FEATURES OF SCOPOLAMINE HYDROBROMIDE INDUCED DRY EYE SYNDROME IN SPRAGUE-DAWLEY RATS" @default.
• W3133922919 cites W1965981953 @default.
• W3133922919 cites W1969004428 @default.
• W3133922919 cites W1972788263 @default.
• W3133922919 cites W1974319067 @default.
• W3133922919 cites W1984965358 @default.
• W3133922919 cites W1996267189 @default.
• W3133922919 cites W2002180108 @default.
• W3133922919 cites W2067655781 @default.
• W3133922919 cites W2078193733 @default.
• W3133922919 cites W2095394089 @default.
• W3133922919 cites W2097527426 @default.
• W3133922919 cites W2109461304 @default.
• W3133922919 cites W2145063462 @default.
• W3133922919 cites W2169772679 @default.
• W3133922919 cites W2728680743 @default.
• W3133922919 cites W2737439597 @default.
• W3133922919 cites W2868111620 @default.
• W3133922919 cites W2898287707 @default.
• W3133922919 cites W2914374322 @default.
• W3133922919 cites W2970366570 @default.
• W3133922919 doi "https://doi.org/10.1142/s1682648520500134" @default.
• W3133922919 hasPublicationYear "2020" @default.
• W3133922919 type Work @default.
• W3133922919 sameAs 3133922919 @default.
• W3133922919 citedByCount "0" @default.
• W3133922919 crossrefType "journal-article" @default.
• W3133922919 hasAuthorship W3133922919A5015879334 @default.
• W3133922919 hasAuthorship W3133922919A5022857093 @default.
• W3133922919 hasAuthorship W3133922919A5028107371 @default.
• W3133922919 hasAuthorship W3133922919A5062845794 @default.
• W3133922919 hasAuthorship W3133922919A5067538672 @default.
• W3133922919 hasAuthorship W3133922919A5072171787 @default.
• W3133922919 hasAuthorship W3133922919A5091845719 @default.
• W3133922919 hasConcept C118487528 @default.
• W3133922919 hasConcept C121332964 @default.
• W3133922919 hasConcept C126322002 @default.
• W3133922919 hasConcept C142724271 @default.
• W3133922919 hasConcept C153400128 @default.
• W3133922919 hasConcept C170493617 @default.
• W3133922919 hasConcept C2776390293 @default.
• W3133922919 hasConcept C2776882836 @default.
• W3133922919 hasConcept C2778015030 @default.
• W3133922919 hasConcept C2778113962 @default.
• W3133922919 hasConcept C2779257441 @default.
• W3133922919 hasConcept C2909050532 @default.
• W3133922919 hasConcept C33789571 @default.
• W3133922919 hasConcept C544855455 @default.
• W3133922919 hasConcept C62520636 @default.
• W3133922919 hasConcept C71924100 @default.
• W3133922919 hasConcept C74864618 @default.
• W3133922919 hasConcept C91881484 @default.
• W3133922919 hasConcept C97355855 @default.
• W3133922919 hasConceptScore W3133922919C118487528 @default.
• W3133922919 hasConceptScore W3133922919C121332964 @default.
• W3133922919 hasConceptScore W3133922919C126322002 @default.
• W3133922919 hasConceptScore W3133922919C142724271 @default.
• W3133922919 hasConceptScore W3133922919C153400128 @default.
• W3133922919 hasConceptScore W3133922919C170493617 @default.
• W3133922919 hasConceptScore W3133922919C2776390293 @default.
• W3133922919 hasConceptScore W3133922919C2776882836 @default.
• W3133922919 hasConceptScore W3133922919C2778015030 @default.
• W3133922919 hasConceptScore W3133922919C2778113962 @default.
• W3133922919 hasConceptScore W3133922919C2779257441 @default.
• W3133922919 hasConceptScore W3133922919C2909050532 @default.
• W3133922919 hasConceptScore W3133922919C33789571 @default.
• W3133922919 hasConceptScore W3133922919C544855455 @default.
• W3133922919 hasConceptScore W3133922919C62520636 @default.
• W3133922919 hasConceptScore W3133922919C71924100 @default.
• W3133922919 hasConceptScore W3133922919C74864618 @default.
• W3133922919 hasConceptScore W3133922919C91881484 @default.
• W3133922919 hasConceptScore W3133922919C97355855 @default.
• W3133922919 hasFunder F4320335989 @default.
• W3133922919 hasLocation W31339229191 @default.
• W3133922919 hasOpenAccess W3133922919 @default.
• W3133922919 hasPrimaryLocation W31339229191 @default.
• W3133922919 hasRelatedWork W10503828 @default.
• W3133922919 hasRelatedWork W1410376 @default.
• W3133922919 hasRelatedWork W17846690 @default.
• W3133922919 hasRelatedWork W181474 @default.
• W3133922919 hasRelatedWork W2955250 @default.
• W3133922919 hasRelatedWork W3118029 @default.
• W3133922919 hasRelatedWork W3180335 @default.
• W3133922919 hasRelatedWork W5648007 @default.
• W3133922919 hasRelatedWork W918717 @default.
• W3133922919 hasRelatedWork W11515913 @default.
• W3133922919 isParatext "false" @default.
• W3133922919 isRetracted "false" @default.
• W3133922919 magId "3133922919" @default.

• next