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- W3133947367 abstract "This study was carried out to investigate the ameliorative effect of L-carnitine on monosodium glutamate (MSG)-induced testicular toxicity in male mice. Sixty adult male mice were randomized into 6 groups (n = 10). In addition, to the control male mice group (Gp1) that orally administered distilled water, Gp2 mice received 150 mg/kg/day L-carnitine for 35 days. Monosodium glutamate (MSG) was orally administered to male mice at doses of 0.3 and 0.6 mg/g body weight individually (Gp3 & Gp4) and in combination with 150 mg/kg body weight of L-carnitine for 35 days (Gp5 & Gp6). The morphometric parameters, histopathological findings and immunohistochemical studies for PCNA, Ki-67 and Claudin-1 of the testis tissue demonstrated that L-carnitineattenuated and ameliorated the alterations in testicular tissues caused by MSG exposure. Conclusions: The findings of the present study indicated that treatment of male mice with L-carnitine banned MSG-induced testicular toxicity by improving testicular structure status." @default.
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- W3133947367 date "2021-01-14" @default.
- W3133947367 modified "2023-09-27" @default.
- W3133947367 title "Testicular Ameliorative Effect of L- Carnitine on Monosodium Glutamate-Induced Testicular Structure Alterations in Male Mice" @default.
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- W3133947367 doi "https://doi.org/10.21608/eajbsd.2021.154503" @default.
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