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- W3134130026 abstract "Adhesion and patterning of cortical neurons on modified glass surfaces was investigated. Patterns of cortical neurons were prepared with a combination of polyethylenimine (PEI) and plasma-deposited fluorocarbon (FC). In addition neurite development and fasciculation of interconnecting neurites between PEI-coated areas was studied. The patterns consisted of PEI-coated circular holes (diameter 150 /spl mu/m) which were initially etched in a FC layer. The separation distance between the PEI-coated circular holes was varied from 10 up to 90 /spl mu/m. This paper shows that the chemical patterns, prepared with a combination of PEI and plasma deposited FC, results in highly compliant patterns of adhering cortical neurons. Furthermore it was shown that interconnecting neurite bundles between neurons on the PEI-coated circular holes were especially present on the pattern with a minimal separation distance (10 /spl mu/m) between the PEI-coated circular holes. In contrast interconnecting neurite bundles were hardly observed on patterns with a maximal separation distance (90 /spl mu/m) between the PEI-coated circular holes." @default.
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- W3134130026 date "2002-11-11" @default.
- W3134130026 modified "2023-09-24" @default.
- W3134130026 title "Adhesion and patterning of cortical neurons on polyethylenimine and fluorocarboncoated surfaces" @default.
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- W3134130026 doi "https://doi.org/10.1109/iembs.2000.898028" @default.
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