Matches in SemOpenAlex for { <https://semopenalex.org/work/W3134202204> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3134202204 abstract "Abstract Background The impact of prior exposure to systemic corticosteroids on COVID-19 severity in patients hospitalized for a SARS-CoV-2 pneumonia is not known. The present study was designed to answer to this question. Methods The population study was the Covid-Clinic-Toul cohort which records data about all hospitalized patients with a positive reverse transcriptase polymerase chain reaction for a SARS-CoV-2 infection at Toulouse University hospital, France. Exposure to systemic corticosteroids was assessed at hospital admission. A propensity score (PS) according to corticosteroid exposure was calculated including comorbidities, clinical, radiological and biological variables that impact COVID-19 severity. The primary outcome was composite, including admission to intensive care unit, need of mechanical ventilation and death occurring during the 14 days after hospital admission. Logistic regression models adjusted for the PS (overlap weighting) provided odds ratios (ORs) and their 95% confidence intervals (95% CIs). Results Overall, 253 patients were included in the study. Median age was 64 years, 140 patients (59.6%) were men and 218 (86.2%) had at least one comorbidity. Seventeen patients (6.7%) were exposed to corticosteroids before hospital admission. Chronic inflammatory disease ( n = 8) was the most frequent indication. One hundred and twenty patients (47.4%) met the composite outcome. In the crude model, the OR of previous exposure to systemic corticosteroids was 1.64; 95% CI: 0.60–4.44. In the adjusted model, it was 1.09 (95% CI: 0.65–1.83). Conclusion Overall, this study provide some evidences for an absence of an increased risk of unfavorable outcome with previous exposure to corticosteroids in the general setting of patients hospitalized for COVID-19." @default.
- W3134202204 created "2021-03-15" @default.
- W3134202204 creator A5004134930 @default.
- W3134202204 creator A5011626280 @default.
- W3134202204 creator A5035903363 @default.
- W3134202204 creator A5040346516 @default.
- W3134202204 creator A5055718888 @default.
- W3134202204 creator A5069068175 @default.
- W3134202204 creator A5069296454 @default.
- W3134202204 date "2021-03-11" @default.
- W3134202204 modified "2023-10-12" @default.
- W3134202204 title "Impact of previous exposure to systemic corticosteroids on unfavorable outcome in patients hospitalized for COVID-19" @default.
- W3134202204 cites W1761464837 @default.
- W3134202204 cites W2143721482 @default.
- W3134202204 cites W2907932858 @default.
- W3134202204 cites W3014663601 @default.
- W3134202204 cites W3021024241 @default.
- W3134202204 cites W3023814660 @default.
- W3134202204 cites W3024016727 @default.
- W3134202204 cites W3024177957 @default.
- W3134202204 cites W3025124391 @default.
- W3134202204 cites W3082355253 @default.
- W3134202204 cites W3091854997 @default.
- W3134202204 cites W3097137658 @default.
- W3134202204 cites W4210642183 @default.
- W3134202204 doi "https://doi.org/10.1186/s40360-021-00480-3" @default.
- W3134202204 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7948656" @default.
- W3134202204 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33706794" @default.
- W3134202204 hasPublicationYear "2021" @default.
- W3134202204 type Work @default.
- W3134202204 sameAs 3134202204 @default.
- W3134202204 citedByCount "7" @default.
- W3134202204 countsByYear W31342022042021 @default.
- W3134202204 countsByYear W31342022042022 @default.
- W3134202204 countsByYear W31342022042023 @default.
- W3134202204 crossrefType "journal-article" @default.
- W3134202204 hasAuthorship W3134202204A5004134930 @default.
- W3134202204 hasAuthorship W3134202204A5011626280 @default.
- W3134202204 hasAuthorship W3134202204A5035903363 @default.
- W3134202204 hasAuthorship W3134202204A5040346516 @default.
- W3134202204 hasAuthorship W3134202204A5055718888 @default.
- W3134202204 hasAuthorship W3134202204A5069068175 @default.
- W3134202204 hasAuthorship W3134202204A5069296454 @default.
- W3134202204 hasBestOaLocation W31342022041 @default.
- W3134202204 hasConcept C126322002 @default.
- W3134202204 hasConcept C151956035 @default.
- W3134202204 hasConcept C156957248 @default.
- W3134202204 hasConcept C17923572 @default.
- W3134202204 hasConcept C2776376669 @default.
- W3134202204 hasConcept C2777080012 @default.
- W3134202204 hasConcept C2777914695 @default.
- W3134202204 hasConcept C2779159551 @default.
- W3134202204 hasConcept C2908647359 @default.
- W3134202204 hasConcept C44249647 @default.
- W3134202204 hasConcept C71924100 @default.
- W3134202204 hasConcept C72563966 @default.
- W3134202204 hasConcept C99454951 @default.
- W3134202204 hasConceptScore W3134202204C126322002 @default.
- W3134202204 hasConceptScore W3134202204C151956035 @default.
- W3134202204 hasConceptScore W3134202204C156957248 @default.
- W3134202204 hasConceptScore W3134202204C17923572 @default.
- W3134202204 hasConceptScore W3134202204C2776376669 @default.
- W3134202204 hasConceptScore W3134202204C2777080012 @default.
- W3134202204 hasConceptScore W3134202204C2777914695 @default.
- W3134202204 hasConceptScore W3134202204C2779159551 @default.
- W3134202204 hasConceptScore W3134202204C2908647359 @default.
- W3134202204 hasConceptScore W3134202204C44249647 @default.
- W3134202204 hasConceptScore W3134202204C71924100 @default.
- W3134202204 hasConceptScore W3134202204C72563966 @default.
- W3134202204 hasConceptScore W3134202204C99454951 @default.
- W3134202204 hasFunder F4320323952 @default.
- W3134202204 hasIssue "1" @default.
- W3134202204 hasLocation W31342022041 @default.
- W3134202204 hasLocation W31342022042 @default.
- W3134202204 hasLocation W31342022043 @default.
- W3134202204 hasLocation W31342022044 @default.
- W3134202204 hasLocation W31342022045 @default.
- W3134202204 hasLocation W31342022046 @default.
- W3134202204 hasOpenAccess W3134202204 @default.
- W3134202204 hasPrimaryLocation W31342022041 @default.
- W3134202204 hasRelatedWork W1989471045 @default.
- W3134202204 hasRelatedWork W1998701987 @default.
- W3134202204 hasRelatedWork W2067415355 @default.
- W3134202204 hasRelatedWork W2228177369 @default.
- W3134202204 hasRelatedWork W2259358466 @default.
- W3134202204 hasRelatedWork W2328123597 @default.
- W3134202204 hasRelatedWork W2335083976 @default.
- W3134202204 hasRelatedWork W2993632815 @default.
- W3134202204 hasRelatedWork W3186334452 @default.
- W3134202204 hasRelatedWork W4292367209 @default.
- W3134202204 hasVolume "22" @default.
- W3134202204 isParatext "false" @default.
- W3134202204 isRetracted "false" @default.
- W3134202204 magId "3134202204" @default.
- W3134202204 workType "article" @default.