Matches in SemOpenAlex for { <https://semopenalex.org/work/W3134278208> ?p ?o ?g. }
- W3134278208 endingPage "4000" @default.
- W3134278208 startingPage "3991" @default.
- W3134278208 abstract "Pancreatic cancer (PC) has been the fourth cancer-related death worldwide, diagnosed at an unresectable stage due to its rapid progression and few symptoms of this disease at early stages. The aim of this study was to determine the association between the diversity of T-cell receptor (TCR) repertoire and clinicopathological characteristics of patients with PC and other benign pancreatic diseases. In order to make a comprehensive analysis the TCR repertoire, high-throughput sequencing was used to differentiate complementarity determining region 3 (CDR3) of the TCR β chain in peripheral blood samples from 3 PC, 3 chronic pancreatitis, 3 pancreatic cystic lesions and 3 pancreatic neuroendocrine tumour patients. We found that there were significant differences related to TCR repertoire between PC and other pancreatic diseases, and PC is a relatively immunosuppressive tumour. Changes of peripheral TCR repertoire may be used to predict the progression of PC and the response to immunotherapy. And there may exist novel-specific antigens in PC patients which could be used to design targeting immunotherapy in the nearly future." @default.
- W3134278208 created "2021-03-15" @default.
- W3134278208 creator A5000723230 @default.
- W3134278208 creator A5005210262 @default.
- W3134278208 creator A5005347770 @default.
- W3134278208 creator A5018324460 @default.
- W3134278208 creator A5027664400 @default.
- W3134278208 creator A5038003812 @default.
- W3134278208 creator A5038291626 @default.
- W3134278208 creator A5039778990 @default.
- W3134278208 creator A5040752319 @default.
- W3134278208 creator A5049290197 @default.
- W3134278208 creator A5051086315 @default.
- W3134278208 creator A5056891933 @default.
- W3134278208 creator A5066562420 @default.
- W3134278208 creator A5073216396 @default.
- W3134278208 creator A5076464007 @default.
- W3134278208 creator A5079686991 @default.
- W3134278208 creator A5084939652 @default.
- W3134278208 creator A5088695098 @default.
- W3134278208 date "2021-03-08" @default.
- W3134278208 modified "2023-10-17" @default.
- W3134278208 title "Analysis of T‐cell receptor repertoire in peripheral blood of patients with pancreatic cancer and other pancreatic diseases" @default.
- W3134278208 cites W1453457571 @default.
- W3134278208 cites W1488069418 @default.
- W3134278208 cites W1966115600 @default.
- W3134278208 cites W1968812902 @default.
- W3134278208 cites W1971620413 @default.
- W3134278208 cites W1980249052 @default.
- W3134278208 cites W1998927848 @default.
- W3134278208 cites W2032166347 @default.
- W3134278208 cites W2051646047 @default.
- W3134278208 cites W2056403357 @default.
- W3134278208 cites W2061123122 @default.
- W3134278208 cites W2101653483 @default.
- W3134278208 cites W2108100098 @default.
- W3134278208 cites W2132290857 @default.
- W3134278208 cites W2141269240 @default.
- W3134278208 cites W2155711520 @default.
- W3134278208 cites W2158804744 @default.
- W3134278208 cites W2160834915 @default.
- W3134278208 cites W2177022639 @default.
- W3134278208 cites W2252550602 @default.
- W3134278208 cites W2260614540 @default.
- W3134278208 cites W2296047035 @default.
- W3134278208 cites W2316210347 @default.
- W3134278208 cites W2320627825 @default.
- W3134278208 cites W2403787004 @default.
- W3134278208 cites W2476535369 @default.
- W3134278208 cites W2560830801 @default.
- W3134278208 cites W2568328220 @default.
- W3134278208 cites W2619463261 @default.
- W3134278208 cites W2889646458 @default.
- W3134278208 cites W2900841241 @default.
- W3134278208 cites W2901888912 @default.
- W3134278208 cites W2915008682 @default.
- W3134278208 cites W2999417355 @default.
- W3134278208 cites W3008769428 @default.
- W3134278208 doi "https://doi.org/10.1111/jcmm.16358" @default.
- W3134278208 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8051704" @default.
- W3134278208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33682267" @default.
- W3134278208 hasPublicationYear "2021" @default.
- W3134278208 type Work @default.
- W3134278208 sameAs 3134278208 @default.
- W3134278208 citedByCount "2" @default.
- W3134278208 countsByYear W31342782082023 @default.
- W3134278208 crossrefType "journal-article" @default.
- W3134278208 hasAuthorship W3134278208A5000723230 @default.
- W3134278208 hasAuthorship W3134278208A5005210262 @default.
- W3134278208 hasAuthorship W3134278208A5005347770 @default.
- W3134278208 hasAuthorship W3134278208A5018324460 @default.
- W3134278208 hasAuthorship W3134278208A5027664400 @default.
- W3134278208 hasAuthorship W3134278208A5038003812 @default.
- W3134278208 hasAuthorship W3134278208A5038291626 @default.
- W3134278208 hasAuthorship W3134278208A5039778990 @default.
- W3134278208 hasAuthorship W3134278208A5040752319 @default.
- W3134278208 hasAuthorship W3134278208A5049290197 @default.
- W3134278208 hasAuthorship W3134278208A5051086315 @default.
- W3134278208 hasAuthorship W3134278208A5056891933 @default.
- W3134278208 hasAuthorship W3134278208A5066562420 @default.
- W3134278208 hasAuthorship W3134278208A5073216396 @default.
- W3134278208 hasAuthorship W3134278208A5076464007 @default.
- W3134278208 hasAuthorship W3134278208A5079686991 @default.
- W3134278208 hasAuthorship W3134278208A5084939652 @default.
- W3134278208 hasAuthorship W3134278208A5088695098 @default.
- W3134278208 hasBestOaLocation W31342782082 @default.
- W3134278208 hasConcept C121332964 @default.
- W3134278208 hasConcept C121608353 @default.
- W3134278208 hasConcept C126322002 @default.
- W3134278208 hasConcept C142724271 @default.
- W3134278208 hasConcept C147483822 @default.
- W3134278208 hasConcept C19317047 @default.
- W3134278208 hasConcept C203014093 @default.
- W3134278208 hasConcept C24890656 @default.
- W3134278208 hasConcept C2775967933 @default.
- W3134278208 hasConcept C2776090121 @default.
- W3134278208 hasConcept C2777701055 @default.
- W3134278208 hasConcept C2778473898 @default.