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• W3134291919 endingPage "104395" @default.
• W3134291919 startingPage "104395" @default.
• W3134291919 abstract "This study characterizes the material properties of a viscoelastic, ex vivo porcine ascending aorta under dynamic-loading conditions via pulsatile flow . The deformation of the opaque vessel wall and the pulsatile flow field inside the vessel were recorded using ultrasound imaging. The internal pressure was extracted from the pulsatile flow results and, when coupled with the vessel-wall expansion, was used to calculate the instantaneous elastic modulus from a novel, time-resolved two-dimensional (i.e. axial and circumferential) stress model. The circumferential instantaneous elasticity obtained from the two-dimensional stress model was found to match the uniaxial tensile test for strains below 50%. The agreement in elasticity between the two stress states reveals that the two-dimensional stress model accurately resolves the circumferential stress of the viscoelastic aorta at physiological strains (8%–30%). At higher strains, results from pulsatile flow generated a more compliant response than the uniaxial measurements. Viscoelastic properties (storage modulus and loss factor) were also calculated using the two-dimensional stress model and compared to those obtained from uniaxial tests. While instantaneous elasticity matched between the cylindrical and uniaxial loading, the viscoelastic behaviour significantly diverged between stress states. The storage modulus obtained from the pulsatile flow data was dependent on mean Reynolds number , while the uniaxial storage modulus results exhibited a strong inverse dependency on the frequency. The loss factor for the pulsatile flow data increased alongside the frequency, while the uniaxial data indicated a constant loss factor over the entire frequency range. The results of the current study show that the two-dimensional stress model can accurately extract the material properties of the ex vivo porcine aorta." @default.
• W3134291919 created "2021-03-15" @default.
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• W3134291919 date "2021-06-01" @default.
• W3134291919 modified "2023-09-29" @default.
• W3134291919 title "Characterization of the dynamic viscoelastic response of the ascending aorta imposed via pulsatile flow" @default.
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• W3134291919 doi "https://doi.org/10.1016/j.jmbbm.2021.104395" @default.
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