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• W3134421837 abstract "Background: The global pandemic caused by novel Coronavirus SARS-CoV-2 disease (COVID-19) is a major threat to the general population and for patients with pre-existing chronic conditions. We report data concerning SARS-CoV-2 infection in children with chronic liver disease (CLD). Methods: A literature review using the online database PubMed was performed to summarize available findings on the association between pre-existing liver disease and COVID-19 infection in children. Results: Children with COVID-19 have preserved effector and immunosuppressive components resulting in a milder disease compared to adults. The most common hepatic manifestation is an elevation of hepatic transaminases. Liver damage may be directly caused by viral infection of liver cells, by medications or by the chronic hypoxia seen in COVID-19 patients. A multicenter study reported that the majority of children with a CLD remained healthy during the outbreak. Similarly, studies reported that children on immunosuppressive treatment, including patients with autoimmune liver disease (AILD) and liver transplantation (LT), maintained good health during the outbreak without experiencing major complications even if infected with COVID-19. Conclusion: COVID-19-related liver injury presents with a mild elevation of transaminases, although its clinical significance is unclear. Children with CLD, including those with AILD and post-LT, do not have an increased risk for severe disease course of SARS-CoV-2 infection with little or no liver dysfunction. These data highlight the necessity to ensure normal standards of care while adhering to national Covid-19 guidelines, and particularly to maintain immunosuppressive medication to prevent relapse or rejection. Further research is required to evaluate the differences in clinical course between immunosuppressed adults and children and in particular whether asymptomatic infection is a concern." @default.
• W3134421837 created "2021-03-15" @default.
• W3134421837 creator A5006405927 @default.
• W3134421837 creator A5022592411 @default.
• W3134421837 creator A5064358518 @default.
• W3134421837 creator A5075439783 @default.
• W3134421837 date "2021-03-11" @default.
• W3134421837 modified "2023-09-24" @default.
• W3134421837 title "COVID-19 in Children With Liver Disease" @default.
• W3134421837 cites W1916127359 @default.
• W3134421837 cites W1956715476 @default.
• W3134421837 cites W2132922192 @default.
• W3134421837 cites W2278898871 @default.
• W3134421837 cites W2525776040 @default.
• W3134421837 cites W2760424869 @default.
• W3134421837 cites W2895314519 @default.
• W3134421837 cites W2910000567 @default.
• W3134421837 cites W2978552283 @default.
• W3134421837 cites W2990634276 @default.
• W3134421837 cites W3001118548 @default.
• W3134421837 cites W3001897055 @default.
• W3134421837 cites W3004662718 @default.
• W3134421837 cites W3008028633 @default.
• W3134421837 cites W3008223050 @default.
• W3134421837 cites W3008827533 @default.
• W3134421837 cites W3009169728 @default.
• W3134421837 cites W3009909056 @default.
• W3134421837 cites W3010637630 @default.
• W3134421837 cites W3011708061 @default.
• W3134421837 cites W3012259277 @default.
• W3134421837 cites W3012421327 @default.
• W3134421837 cites W3012619627 @default.
• W3134421837 cites W3013000795 @default.
• W3134421837 cites W3013250171 @default.
• W3134421837 cites W3013334176 @default.
• W3134421837 cites W3013616922 @default.
• W3134421837 cites W3013727805 @default.
• W3134421837 cites W3014117069 @default.
• W3134421837 cites W3014918660 @default.
• W3134421837 cites W3015202928 @default.
• W3134421837 cites W3015221761 @default.
• W3134421837 cites W3015256585 @default.
• W3134421837 cites W3015444032 @default.
• W3134421837 cites W3015899180 @default.
• W3134421837 cites W3016139359 @default.
• W3134421837 cites W3016151265 @default.
• W3134421837 cites W3016474181 @default.
• W3134421837 cites W3016570462 @default.
• W3134421837 cites W3018047057 @default.
• W3134421837 cites W3018726064 @default.
• W3134421837 cites W3019031660 @default.
• W3134421837 cites W3019527508 @default.
• W3134421837 cites W3020892262 @default.
• W3134421837 cites W3021577619 @default.
• W3134421837 cites W3021716051 @default.
• W3134421837 cites W3022972552 @default.
• W3134421837 cites W3023701654 @default.
• W3134421837 cites W3024021631 @default.
• W3134421837 cites W3024187395 @default.
• W3134421837 cites W3024339709 @default.
• W3134421837 cites W3025210114 @default.
• W3134421837 cites W3025844765 @default.
• W3134421837 cites W3027111164 @default.
• W3134421837 cites W3027630905 @default.
• W3134421837 cites W3027837984 @default.
• W3134421837 cites W3027948254 @default.
• W3134421837 cites W3029599334 @default.
• W3134421837 cites W3030272834 @default.
• W3134421837 cites W3030384525 @default.
• W3134421837 cites W3030684905 @default.
• W3134421837 cites W3031362785 @default.
• W3134421837 cites W3031459380 @default.
• W3134421837 cites W3031713879 @default.
• W3134421837 cites W3032543466 @default.
• W3134421837 cites W3032940926 @default.
• W3134421837 cites W3032971139 @default.
• W3134421837 cites W3033189130 @default.
• W3134421837 cites W3033880976 @default.
• W3134421837 cites W3034089332 @default.
• W3134421837 cites W3034308804 @default.
• W3134421837 cites W3034561954 @default.
• W3134421837 cites W3035857377 @default.
• W3134421837 cites W3036454083 @default.
• W3134421837 cites W3036799426 @default.
• W3134421837 cites W3037158712 @default.
• W3134421837 cites W3037647368 @default.
• W3134421837 cites W3038175434 @default.
• W3134421837 cites W3038958209 @default.
• W3134421837 cites W3039113963 @default.
• W3134421837 cites W3040477964 @default.
• W3134421837 cites W3041858648 @default.
• W3134421837 cites W3041881467 @default.
• W3134421837 cites W3042066663 @default.
• W3134421837 cites W3042516758 @default.
• W3134421837 cites W3043433796 @default.
• W3134421837 cites W3044536727 @default.
• W3134421837 cites W3046256437 @default.
• W3134421837 cites W3046501796 @default.
• W3134421837 cites W3048866311 @default.
• W3134421837 cites W3081207810 @default.

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