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- W3134637781 abstract "ABSTRACT Executing memory-guided behavior requires both the storage of information about experience and the later recall of that information to inform choices. Awake hippocampal replay, when hippocampal neural ensembles briefly reactivate a representation related to prior experience, has been proposed to critically contribute to these memory-related processes. However, it remains unclear whether awake replay contributes to memory function by promoting the storage of past experiences, by facilitating planning based on an evaluation of those experiences, or both. We designed a dynamic spatial task which promotes replay before a memory-based choice and assessed how the content of replay related to past and future behavior. We found that replay content was decoupled from subsequent choice and instead was enriched for representations of previously rewarded locations and places that had not been recently visited, indicating a role in memory storage rather than in directly guiding subsequent behavior." @default.
- W3134637781 created "2021-03-15" @default.
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- W3134637781 date "2021-03-10" @default.
- W3134637781 modified "2023-09-30" @default.
- W3134637781 title "Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice" @default.
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- W3134637781 doi "https://doi.org/10.1101/2021.03.09.434621" @default.
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