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• W3134712918 endingPage "110935" @default.
• W3134712918 startingPage "110935" @default.
• W3134712918 abstract "In previous studies we demonstrated that radiofrequency (RF) electromagnetic fields (EMF) is able to reduce DNA damage induced by a subsequent treatment with genotoxic agents, resembling the adaptive response, a phenomenon well known in radiobiology. In this study we report on the capability of the culture medium from SH-SY5Y neuroblastoma cells exposed to 1950 MHz to elicit, in recipient non-exposed cells, a reduction of menadione-induced DNA damage (P < 0.05; comet assay), indicating the capability of non-ionizing radiation to elicit a bystander effect. A comparable reduction was also detected in cultures directly exposed to the same EMF conditions (P < 0.05), confirming the adaptive response. In the same exposure conditions, we also evidenced an increase of heat shock protein 70 (hsp70) in culture medium of cells exposed to RF with respect to sham exposed ones (P < 0.05; western blot analysis), while no differences were detected in the intracellular content of hsp70. On the whole, our results evidence a protective effect of RF against menadione-induced DNA damage in directly and non-directly exposed cells, and suggest hsp70 pathway to be investigated as one of the potential candidate underpinning the interaction between RF exposure and biological systems." @default.
• W3134712918 created "2021-03-15" @default.
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• W3134712918 date "2021-05-01" @default.
• W3134712918 modified "2023-10-09" @default.
• W3134712918 title "Evidence of bystander effect induced by radiofrequency radiation in a human neuroblastoma cell line" @default.
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• W3134712918 doi "https://doi.org/10.1016/j.envres.2021.110935" @default.
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• W3134712918 hasPublicationYear "2021" @default.
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