Matches in SemOpenAlex for { <https://semopenalex.org/work/W3134718230> ?p ?o ?g. }
- W3134718230 endingPage "2005155" @default.
- W3134718230 startingPage "2005155" @default.
- W3134718230 abstract "Anti-angiogenic therapy, targeting vascular endothelial cells (ECs) to prevent tumor growth, has been attracting increasing attention in recent years, beginning with bevacizumab (Avastin) through its Phase II/III clinical trials on solid tumors. However, these trials showed only modest clinical efficiency; moreover, anti-angiogenic therapy may induce acquired resistance to the drugs employed. Combining advanced drug delivery techniques (e.g., nanotechnology) or other therapeutic strategies (e.g., chemotherapy, radiotherapy, phototherapy, and immunotherapy) with anti-angiogenic therapy results in significantly synergistic effects and has opened a new horizon in fighting cancer. Herein, clinical difficulties in using traditional anti-angiogenic therapy are discussed. Then, several promising applications of anti-angiogenic nanoagents in monotherapies and combination therapies are highlighted. Finally, the challenges and perspectives of anti-angiogenic cancer therapy are summarized. A useful introduction to anti-angiogenic strategies, which may significantly improve therapeutic outcomes, is thus provided." @default.
- W3134718230 created "2021-03-15" @default.
- W3134718230 creator A5001636097 @default.
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- W3134718230 creator A5087996919 @default.
- W3134718230 date "2021-03-08" @default.
- W3134718230 modified "2023-10-11" @default.
- W3134718230 title "Monotherapy and Combination Therapy Using Anti‐Angiogenic Nanoagents to Fight Cancer" @default.
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