FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3134729812> ?p ?o ?g. }

• W3134729812 endingPage "1158" @default.
• W3134729812 startingPage "1151" @default.
• W3134729812 abstract "Purpose This study aimed to find indicators for early response to radiation therapy in breast cancer. These would be of help in tailoring treatment for individual patients. Methods and Materials We analyzed 66 patients with low-risk breast cancer (≥60 years; cT1-2pN0) treated within the Preoperative Accelerated Partial Breast Irradiation (PAPBI) trial. Patients received radiation therapy (RT; 10 x 4 Gray or 5 x 6 Gray), followed by a wide local excision after 6 weeks. Patients underwent magnetic resonance imaging (MRI) and 18F-fluorodexoyglucose (FDG) positron emission tomography/computed tomography (PET/CT) before RT and 5 weeks after RT, before surgery. We assessed the response to PAPBI using a histopathologic assessment and correlated this with responses on MRI and FDG PET/CT. We calculated the positive predictive values (PPVs) of MRI and PET/CT as the number of true positives (complete response on MRI/normalized at visual evaluation on PET/CT and pathologic complete response) divided by the number of patients with a complete response on MRI/normalized at visual evaluation on PET/CT. Similarly, the negative predictive values (NPVs) of MRI and PET/CT were calculated. Results The pathologic response was (nearly) complete in 15 (23%) of the 66 patients and partially complete in 28 (42%). The remaining 23 patients (35%) were nonresponders. The PPV of MRI (Response evaluation criteria in solid tumors [RECIST]) was 87.5% and the NPV was 85%. The PPV and NPV of PET/CT were 25% and 92%, respectively. Conclusions The most accurate method to predict a response and residual disease after preoperative RT in low-risk breast cancer was MRI, using RECIST. This study aimed to find indicators for early response to radiation therapy in breast cancer. These would be of help in tailoring treatment for individual patients. We analyzed 66 patients with low-risk breast cancer (≥60 years; cT1-2pN0) treated within the Preoperative Accelerated Partial Breast Irradiation (PAPBI) trial. Patients received radiation therapy (RT; 10 x 4 Gray or 5 x 6 Gray), followed by a wide local excision after 6 weeks. Patients underwent magnetic resonance imaging (MRI) and 18F-fluorodexoyglucose (FDG) positron emission tomography/computed tomography (PET/CT) before RT and 5 weeks after RT, before surgery. We assessed the response to PAPBI using a histopathologic assessment and correlated this with responses on MRI and FDG PET/CT. We calculated the positive predictive values (PPVs) of MRI and PET/CT as the number of true positives (complete response on MRI/normalized at visual evaluation on PET/CT and pathologic complete response) divided by the number of patients with a complete response on MRI/normalized at visual evaluation on PET/CT. Similarly, the negative predictive values (NPVs) of MRI and PET/CT were calculated. The pathologic response was (nearly) complete in 15 (23%) of the 66 patients and partially complete in 28 (42%). The remaining 23 patients (35%) were nonresponders. The PPV of MRI (Response evaluation criteria in solid tumors [RECIST]) was 87.5% and the NPV was 85%. The PPV and NPV of PET/CT were 25% and 92%, respectively. The most accurate method to predict a response and residual disease after preoperative RT in low-risk breast cancer was MRI, using RECIST." @default.
• W3134729812 created "2021-03-15" @default.
• W3134729812 creator A5016632019 @default.
• W3134729812 creator A5024540647 @default.
• W3134729812 creator A5046853252 @default.
• W3134729812 creator A5051021152 @default.
• W3134729812 creator A5063757732 @default.
• W3134729812 creator A5068453772 @default.
• W3134729812 creator A5068893119 @default.
• W3134729812 creator A5089839279 @default.
• W3134729812 date "2021-07-01" @default.
• W3134729812 modified "2023-10-02" @default.
• W3134729812 title "Evaluation of Early Response to Preoperative Accelerated Partial Breast Irradiation (PAPBI) by Histopathology, Magnetic Resonance Imaging, and 18F-fluorodexoyglucose Positron Emission Tomography/Computed Tomography (FDG PET/CT)" @default.
• W3134729812 cites W1957419510 @default.
• W3134729812 cites W2001799948 @default.
• W3134729812 cites W2006816753 @default.
• W3134729812 cites W2009227369 @default.
• W3134729812 cites W2019607817 @default.
• W3134729812 cites W2023494838 @default.
• W3134729812 cites W2050761481 @default.
• W3134729812 cites W2053074390 @default.
• W3134729812 cites W2075894019 @default.
• W3134729812 cites W2086960359 @default.
• W3134729812 cites W2097313333 @default.
• W3134729812 cites W2098299197 @default.
• W3134729812 cites W2100025800 @default.
• W3134729812 cites W2118404651 @default.
• W3134729812 cites W2119549339 @default.
• W3134729812 cites W2127652790 @default.
• W3134729812 cites W2140978771 @default.
• W3134729812 cites W2150539933 @default.
• W3134729812 cites W2153369531 @default.
• W3134729812 cites W2156681954 @default.
• W3134729812 cites W2166457180 @default.
• W3134729812 cites W2167353413 @default.
• W3134729812 cites W2171015116 @default.
• W3134729812 cites W2295340876 @default.
• W3134729812 cites W2555240095 @default.
• W3134729812 cites W2619681408 @default.
• W3134729812 cites W2731714044 @default.
• W3134729812 cites W2742020913 @default.
• W3134729812 cites W2758176523 @default.
• W3134729812 cites W2991896238 @default.
• W3134729812 cites W3001515809 @default.
• W3134729812 cites W3034125817 @default.
• W3134729812 doi "https://doi.org/10.1016/j.ijrobp.2021.02.033" @default.
• W3134729812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33647369" @default.
• W3134729812 hasPublicationYear "2021" @default.
• W3134729812 type Work @default.
• W3134729812 sameAs 3134729812 @default.
• W3134729812 citedByCount "5" @default.
• W3134729812 countsByYear W31347298122022 @default.
• W3134729812 countsByYear W31347298122023 @default.
• W3134729812 crossrefType "journal-article" @default.
• W3134729812 hasAuthorship W3134729812A5016632019 @default.
• W3134729812 hasAuthorship W3134729812A5024540647 @default.
• W3134729812 hasAuthorship W3134729812A5046853252 @default.
• W3134729812 hasAuthorship W3134729812A5051021152 @default.
• W3134729812 hasAuthorship W3134729812A5063757732 @default.
• W3134729812 hasAuthorship W3134729812A5068453772 @default.
• W3134729812 hasAuthorship W3134729812A5068893119 @default.
• W3134729812 hasAuthorship W3134729812A5089839279 @default.
• W3134729812 hasConcept C121608353 @default.
• W3134729812 hasConcept C126322002 @default.
• W3134729812 hasConcept C126838900 @default.
• W3134729812 hasConcept C127077266 @default.
• W3134729812 hasConcept C143409427 @default.
• W3134729812 hasConcept C2775842073 @default.
• W3134729812 hasConcept C2989005 @default.
• W3134729812 hasConcept C37097830 @default.
• W3134729812 hasConcept C509974204 @default.
• W3134729812 hasConcept C530470458 @default.
• W3134729812 hasConcept C71924100 @default.
• W3134729812 hasConceptScore W3134729812C121608353 @default.
• W3134729812 hasConceptScore W3134729812C126322002 @default.
• W3134729812 hasConceptScore W3134729812C126838900 @default.
• W3134729812 hasConceptScore W3134729812C127077266 @default.
• W3134729812 hasConceptScore W3134729812C143409427 @default.
• W3134729812 hasConceptScore W3134729812C2775842073 @default.
• W3134729812 hasConceptScore W3134729812C2989005 @default.
• W3134729812 hasConceptScore W3134729812C37097830 @default.
• W3134729812 hasConceptScore W3134729812C509974204 @default.
• W3134729812 hasConceptScore W3134729812C530470458 @default.
• W3134729812 hasConceptScore W3134729812C71924100 @default.
• W3134729812 hasFunder F4320322777 @default.
• W3134729812 hasIssue "4" @default.
• W3134729812 hasLocation W31347298121 @default.
• W3134729812 hasOpenAccess W3134729812 @default.
• W3134729812 hasPrimaryLocation W31347298121 @default.
• W3134729812 hasRelatedWork W1965188844 @default.
• W3134729812 hasRelatedWork W2021569957 @default.
• W3134729812 hasRelatedWork W2080502759 @default.
• W3134729812 hasRelatedWork W219766168 @default.
• W3134729812 hasRelatedWork W2519926401 @default.
• W3134729812 hasRelatedWork W2606589899 @default.
• W3134729812 hasRelatedWork W2731120814 @default.
• W3134729812 hasRelatedWork W2913624518 @default.
• W3134729812 hasRelatedWork W2976224709 @default.

• next