Matches in SemOpenAlex for { <https://semopenalex.org/work/W3134731355> ?p ?o ?g. }
- W3134731355 abstract "Abstract Background The synchrony between the embryo and the receptive endometrium is essential for successful implantation. Therefore, a reliable non-invasive ER prediction method is highly demanded. We aimed to establish a method that could be used to predict endometrium receptivity non-invasively and to evaluate its clinical application potential in patients undergoing IVF. Methods The non-invasive RNA-seq based endometrial receptivity test (nirsERT) was established by sequencing and analyzing the RNA of uterine fluid from 48 IVF patients with normal ER. Subsequently, 22 IVF patients were recruited and analyzed the correlation between the predicted results of nirsERT and pregnancy outcomes. Results 87 marker genes and 3 hub genes were selected to establish the nirsERT. 10-fold cross-validation resulted in a mean accuracy of 93.0%. A small cohort retrospective observation showed that 77.8% (14/18) of IVF patients predicted with normal WOI had successful intrauterine pregnancies, while none of the 3 patients with displaced WOI had successful pregnancy. Conclusions nirsERT is potential for a non-invasive, accurate and same cycle testing for ER in reproductive clinic. Funding Funded by the National Natural Science Foundation of China (grant no. 8187061497) and the National Key Research and Developmental Program of China (grant no. 2018YFC1004800). Clinical trial number ChiCTR-DDD-17013375." @default.
- W3134731355 created "2021-03-15" @default.
- W3134731355 creator A5000171141 @default.
- W3134731355 creator A5008230312 @default.
- W3134731355 creator A5008250760 @default.
- W3134731355 creator A5015792001 @default.
- W3134731355 creator A5018725045 @default.
- W3134731355 creator A5023290498 @default.
- W3134731355 creator A5030967805 @default.
- W3134731355 creator A5036467990 @default.
- W3134731355 creator A5039539317 @default.
- W3134731355 creator A5046262151 @default.
- W3134731355 creator A5049063282 @default.
- W3134731355 creator A5053743858 @default.
- W3134731355 creator A5057584181 @default.
- W3134731355 creator A5066748214 @default.
- W3134731355 creator A5075542108 @default.
- W3134731355 creator A5077484550 @default.
- W3134731355 creator A5079301669 @default.
- W3134731355 creator A5085698827 @default.
- W3134731355 creator A5085818426 @default.
- W3134731355 date "2021-03-09" @default.
- W3134731355 modified "2023-09-26" @default.
- W3134731355 title "Uterine fluid transcriptome as potential non-invasive biomarker for predicting endometrial receptivity" @default.
- W3134731355 cites W1978918749 @default.
- W3134731355 cites W1983897480 @default.
- W3134731355 cites W1993866784 @default.
- W3134731355 cites W2008264512 @default.
- W3134731355 cites W2019378351 @default.
- W3134731355 cites W2029295976 @default.
- W3134731355 cites W2035693178 @default.
- W3134731355 cites W2049426088 @default.
- W3134731355 cites W2053571583 @default.
- W3134731355 cites W2060705109 @default.
- W3134731355 cites W2069902854 @default.
- W3134731355 cites W2073842961 @default.
- W3134731355 cites W2082230878 @default.
- W3134731355 cites W2086472228 @default.
- W3134731355 cites W2097443687 @default.
- W3134731355 cites W2107861249 @default.
- W3134731355 cites W2124156734 @default.
- W3134731355 cites W2127368795 @default.
- W3134731355 cites W2132214692 @default.
- W3134731355 cites W2153407128 @default.
- W3134731355 cites W2159675211 @default.
- W3134731355 cites W2160327376 @default.
- W3134731355 cites W2161479512 @default.
- W3134731355 cites W2257981973 @default.
- W3134731355 cites W2613629789 @default.
- W3134731355 cites W2747027045 @default.
- W3134731355 cites W2747531951 @default.
- W3134731355 cites W2790395560 @default.
- W3134731355 cites W2810370891 @default.
- W3134731355 cites W2910025422 @default.
- W3134731355 cites W2910521135 @default.
- W3134731355 cites W2965181622 @default.
- W3134731355 cites W2971809390 @default.
- W3134731355 cites W2980847177 @default.
- W3134731355 cites W4239383155 @default.
- W3134731355 doi "https://doi.org/10.1101/2021.03.07.21253097" @default.
- W3134731355 hasPublicationYear "2021" @default.
- W3134731355 type Work @default.
- W3134731355 sameAs 3134731355 @default.
- W3134731355 citedByCount "0" @default.
- W3134731355 crossrefType "posted-content" @default.
- W3134731355 hasAuthorship W3134731355A5000171141 @default.
- W3134731355 hasAuthorship W3134731355A5008230312 @default.
- W3134731355 hasAuthorship W3134731355A5008250760 @default.
- W3134731355 hasAuthorship W3134731355A5015792001 @default.
- W3134731355 hasAuthorship W3134731355A5018725045 @default.
- W3134731355 hasAuthorship W3134731355A5023290498 @default.
- W3134731355 hasAuthorship W3134731355A5030967805 @default.
- W3134731355 hasAuthorship W3134731355A5036467990 @default.
- W3134731355 hasAuthorship W3134731355A5039539317 @default.
- W3134731355 hasAuthorship W3134731355A5046262151 @default.
- W3134731355 hasAuthorship W3134731355A5049063282 @default.
- W3134731355 hasAuthorship W3134731355A5053743858 @default.
- W3134731355 hasAuthorship W3134731355A5057584181 @default.
- W3134731355 hasAuthorship W3134731355A5066748214 @default.
- W3134731355 hasAuthorship W3134731355A5075542108 @default.
- W3134731355 hasAuthorship W3134731355A5077484550 @default.
- W3134731355 hasAuthorship W3134731355A5079301669 @default.
- W3134731355 hasAuthorship W3134731355A5085698827 @default.
- W3134731355 hasAuthorship W3134731355A5085818426 @default.
- W3134731355 hasBestOaLocation W31347313551 @default.
- W3134731355 hasConcept C126322002 @default.
- W3134731355 hasConcept C131872663 @default.
- W3134731355 hasConcept C2776210078 @default.
- W3134731355 hasConcept C2777688143 @default.
- W3134731355 hasConcept C2779234561 @default.
- W3134731355 hasConcept C2779742232 @default.
- W3134731355 hasConcept C2781197716 @default.
- W3134731355 hasConcept C29456083 @default.
- W3134731355 hasConcept C500014431 @default.
- W3134731355 hasConcept C54355233 @default.
- W3134731355 hasConcept C55493867 @default.
- W3134731355 hasConcept C71924100 @default.
- W3134731355 hasConcept C72563966 @default.
- W3134731355 hasConcept C86803240 @default.
- W3134731355 hasConceptScore W3134731355C126322002 @default.