Matches in SemOpenAlex for { <https://semopenalex.org/work/W3134742014> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W3134742014 endingPage "17" @default.
- W3134742014 startingPage "12" @default.
- W3134742014 abstract "Objective: To assess the non-invasive biomarkers of fibrosis for predicting varices-needing-treatment in patients with cirrhosis secondary to chronic-hepatitis-C.
 Study Design: Cross sectional comparative study.
 Place and Duration of Study: Department of Gastroenterology, Pak Emirates Military Hospital Rawalpindi, from Jan 2017 to Dec 2017.
 Methodology: A total of 153 patients aged 18-79 with cirrhosis, whether compensated or decompensated, secondary to chronic-hepatitis-C were enrolled. Relevant serum tests were used to calculate non-invasive fibrosis indices and their diagnostic performance to predict the presence of varices and varices-needing-treatment was calculated.
 Results: King’s score showed the best performance in detecting varices due to high positive predictive value of 96.4% and positive likelihood ratio of 2.4. Overall, all the non-invasive fibrosis indices exhibited good performance with positive predictive value >85% but none could rule out the presence of varices with adequate reliability due to low negative-predictive-value (<65%). King’s score exhibited relatively higher positive-predictivevalue (70%) and negative predictive value (51.1%) and the lowest negative-likelihood-ratio (0.6) for predicting varices needing treatment. Taken together, none of the non-invasive biomarkers of fibrosis could predict the presence of varices-needing-treatment with adequate accuracy due to low positive-predictive-value (<85%) andlow negative-predictive-value (<65%).
 Conclusion: The calculated non-invasive biomarkers of fibrosis and their optimum cutoff values showed modest accuracy for predicting varices and varices-needing-treatment. These indices may be used as first-line screening method for segregation of clinically significant portal hypertension and high risk esophageal varices-needingtreatment but may not be able to replace the gold standards like Fibroscan liver and Hepatic Venous Pressure Gradient measurements." @default.
- W3134742014 created "2021-03-15" @default.
- W3134742014 creator A5003367833 @default.
- W3134742014 creator A5004817894 @default.
- W3134742014 date "2021-02-23" @default.
- W3134742014 modified "2023-10-06" @default.
- W3134742014 title "NON-INVASIVE TOOLS TO ASSESS THE RISK OF VARICES-NEEDING-TREATMENT IN CIRRHOSIS SECONDARY TO HCV" @default.
- W3134742014 doi "https://doi.org/10.51253/pafmj.v71i1.6352" @default.
- W3134742014 hasPublicationYear "2021" @default.
- W3134742014 type Work @default.
- W3134742014 sameAs 3134742014 @default.
- W3134742014 citedByCount "1" @default.
- W3134742014 countsByYear W31347420142022 @default.
- W3134742014 crossrefType "journal-article" @default.
- W3134742014 hasAuthorship W3134742014A5003367833 @default.
- W3134742014 hasAuthorship W3134742014A5004817894 @default.
- W3134742014 hasBestOaLocation W31347420141 @default.
- W3134742014 hasConcept C126322002 @default.
- W3134742014 hasConcept C203014093 @default.
- W3134742014 hasConcept C2522874641 @default.
- W3134742014 hasConcept C2776455275 @default.
- W3134742014 hasConcept C2777214474 @default.
- W3134742014 hasConcept C2778012290 @default.
- W3134742014 hasConcept C2778808290 @default.
- W3134742014 hasConcept C2780559512 @default.
- W3134742014 hasConcept C3019719930 @default.
- W3134742014 hasConcept C3020491458 @default.
- W3134742014 hasConcept C71924100 @default.
- W3134742014 hasConcept C90924648 @default.
- W3134742014 hasConceptScore W3134742014C126322002 @default.
- W3134742014 hasConceptScore W3134742014C203014093 @default.
- W3134742014 hasConceptScore W3134742014C2522874641 @default.
- W3134742014 hasConceptScore W3134742014C2776455275 @default.
- W3134742014 hasConceptScore W3134742014C2777214474 @default.
- W3134742014 hasConceptScore W3134742014C2778012290 @default.
- W3134742014 hasConceptScore W3134742014C2778808290 @default.
- W3134742014 hasConceptScore W3134742014C2780559512 @default.
- W3134742014 hasConceptScore W3134742014C3019719930 @default.
- W3134742014 hasConceptScore W3134742014C3020491458 @default.
- W3134742014 hasConceptScore W3134742014C71924100 @default.
- W3134742014 hasConceptScore W3134742014C90924648 @default.
- W3134742014 hasIssue "1" @default.
- W3134742014 hasLocation W31347420141 @default.
- W3134742014 hasLocation W31347420142 @default.
- W3134742014 hasLocation W31347420143 @default.
- W3134742014 hasOpenAccess W3134742014 @default.
- W3134742014 hasPrimaryLocation W31347420141 @default.
- W3134742014 hasRelatedWork W1971777968 @default.
- W3134742014 hasRelatedWork W1983046387 @default.
- W3134742014 hasRelatedWork W2003787159 @default.
- W3134742014 hasRelatedWork W2014342566 @default.
- W3134742014 hasRelatedWork W2029185255 @default.
- W3134742014 hasRelatedWork W2127836464 @default.
- W3134742014 hasRelatedWork W2164031347 @default.
- W3134742014 hasRelatedWork W2333105868 @default.
- W3134742014 hasRelatedWork W2404561423 @default.
- W3134742014 hasRelatedWork W3031808649 @default.
- W3134742014 hasVolume "71" @default.
- W3134742014 isParatext "false" @default.
- W3134742014 isRetracted "false" @default.
- W3134742014 magId "3134742014" @default.
- W3134742014 workType "article" @default.