FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3134767661> ?p ?o ?g. }

• W3134767661 abstract "Canine atopic dermatitis (AD) is a multifactorial allergic disease associated with immune and abnormal skin barrier dysfunction and it is one of the primary causes of pruritus. Using a novel in vitro model of AD, here we tried to revert the alteration of transcriptional regulation of AD canine key genes testing a nutraceutical mixture containing flavonoids, stilbene, and cannabinoids, which are already well-known for their applications within dermatology diseases. The nutraceutical mixture induced in inflamed cells a significant downregulation ( p &lt; 0.05) of the gene expression of ccl2, ccl17 , and tslp in keratinocytes and of ccl2, ccl17 , and il31ra in monocytes. Consistent with the observed alterations of tslp, ccl2, ccl17 , and il31ra messenger RNA (mRNA) levels, a significant increase ( p &lt; 0.05) of DNA methylation at specific CpG sites on the gene regulatory regions was found. These results lay the foundation for the use of these natural bioactives in veterinary medicine and provide a model for deeper understanding of their mechanisms of action, with potential translation to human research." @default.
• W3134767661 created "2021-03-15" @default.
• W3134767661 creator A5000235221 @default.
• W3134767661 creator A5002401825 @default.
• W3134767661 creator A5012432637 @default.
• W3134767661 creator A5072480911 @default.
• W3134767661 creator A5073036129 @default.
• W3134767661 creator A5079782200 @default.
• W3134767661 creator A5082575375 @default.
• W3134767661 date "2021-03-05" @default.
• W3134767661 modified "2023-10-15" @default.
• W3134767661 title "Polyphenols and Cannabidiol Modulate Transcriptional Regulation of Th1/Th2 Inflammatory Genes Related to Canine Atopic Dermatitis" @default.
• W3134767661 cites W1549140793 @default.
• W3134767661 cites W1914622032 @default.
• W3134767661 cites W1974007432 @default.
• W3134767661 cites W1976639539 @default.
• W3134767661 cites W1976734090 @default.
• W3134767661 cites W1983257136 @default.
• W3134767661 cites W1986250542 @default.
• W3134767661 cites W1998439798 @default.
• W3134767661 cites W2009225247 @default.
• W3134767661 cites W2009645092 @default.
• W3134767661 cites W2019402966 @default.
• W3134767661 cites W2019540415 @default.
• W3134767661 cites W2026124542 @default.
• W3134767661 cites W2035038992 @default.
• W3134767661 cites W2089129679 @default.
• W3134767661 cites W2103819355 @default.
• W3134767661 cites W2113838878 @default.
• W3134767661 cites W2115648838 @default.
• W3134767661 cites W2154288468 @default.
• W3134767661 cites W2221324000 @default.
• W3134767661 cites W2316981948 @default.
• W3134767661 cites W2317148373 @default.
• W3134767661 cites W2346589153 @default.
• W3134767661 cites W2491281233 @default.
• W3134767661 cites W2512332603 @default.
• W3134767661 cites W2537143772 @default.
• W3134767661 cites W2555297165 @default.
• W3134767661 cites W2604389567 @default.
• W3134767661 cites W2739240705 @default.
• W3134767661 cites W2739425417 @default.
• W3134767661 cites W2783884386 @default.
• W3134767661 cites W2792195584 @default.
• W3134767661 cites W2793045501 @default.
• W3134767661 cites W2796408284 @default.
• W3134767661 cites W2796803789 @default.
• W3134767661 cites W2802832468 @default.
• W3134767661 cites W2805582187 @default.
• W3134767661 cites W2830677586 @default.
• W3134767661 cites W2846061873 @default.
• W3134767661 cites W2885212705 @default.
• W3134767661 cites W2889683825 @default.
• W3134767661 cites W2892134681 @default.
• W3134767661 cites W2893973032 @default.
• W3134767661 cites W2896385011 @default.
• W3134767661 cites W2898173461 @default.
• W3134767661 cites W2898401780 @default.
• W3134767661 cites W2899052178 @default.
• W3134767661 cites W2904366212 @default.
• W3134767661 cites W2904547055 @default.
• W3134767661 cites W2908577821 @default.
• W3134767661 cites W2909766986 @default.
• W3134767661 cites W2911150203 @default.
• W3134767661 cites W2913292104 @default.
• W3134767661 cites W2919977311 @default.
• W3134767661 cites W2920359145 @default.
• W3134767661 cites W2920821891 @default.
• W3134767661 cites W2942908650 @default.
• W3134767661 cites W2943211034 @default.
• W3134767661 cites W2945976306 @default.
• W3134767661 cites W2953709808 @default.
• W3134767661 cites W2954329608 @default.
• W3134767661 cites W2969512739 @default.
• W3134767661 cites W2975912975 @default.
• W3134767661 cites W2979619560 @default.
• W3134767661 cites W2987824242 @default.
• W3134767661 cites W2996249945 @default.
• W3134767661 cites W3000524409 @default.
• W3134767661 cites W3012113993 @default.
• W3134767661 cites W3014804384 @default.
• W3134767661 cites W3023890568 @default.
• W3134767661 cites W3045838295 @default.
• W3134767661 cites W3046700090 @default.
• W3134767661 cites W3096578840 @default.
• W3134767661 doi "https://doi.org/10.3389/fvets.2021.606197" @default.
• W3134767661 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7982812" @default.
• W3134767661 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33763461" @default.
• W3134767661 hasPublicationYear "2021" @default.
• W3134767661 type Work @default.
• W3134767661 sameAs 3134767661 @default.
• W3134767661 citedByCount "15" @default.
• W3134767661 countsByYear W31347676612021 @default.
• W3134767661 countsByYear W31347676612022 @default.
• W3134767661 countsByYear W31347676612023 @default.
• W3134767661 crossrefType "journal-article" @default.
• W3134767661 hasAuthorship W3134767661A5000235221 @default.
• W3134767661 hasAuthorship W3134767661A5002401825 @default.
• W3134767661 hasAuthorship W3134767661A5012432637 @default.
• W3134767661 hasAuthorship W3134767661A5072480911 @default.

• next