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• W3134939064 abstract "Rationale : The prevalence of malformation of internal carotid arteries (ICA) in the population amounts to 46%. In 4 to 16% of the cases, it is associated with clinical manifestations of cerebrovascular insufficiency. Hemodynamic changes in the abnormal arterial vasculature and neurological symptoms are the main indications for surgical intervention. Computed tomography (CT) angiography has shown its high information value in the assessment of ICA occlusions; however, its informativity in the diagnosis of ICA malformations has not been established. Aim : To assess ICA and brain matter in the patients with abnormal tortuosities, both isolated and combined with occlusion, by CT angiography. Materials and methods : We performed a retrospective analysis of medical files of 58 inpatients, who underwent ultrasound examination and CT angiography of extra and intracranial parts of brachycephalic arteries with 256 slice multidetector computer scanner (Philips iCT). CT angiography included native imaging, and contrast-enhanced arterial and venous phases. We assessed the impact of ICA abnormalities on the degree of brain matter lesions in patients with isolated ICA malformations (n=27) and with combination of ICA malformations with its occlusion (n=31). Results : In the group of the patients with isolated ICA malformations, there were no brain focal lesions in 14, small vessel focal lesions and single liquor cysts in 9, and areas and zones of cystic and glial abnormalities in 4. The most frequent in this group were S-like and C-like malformations, together with 2 saccular aneurysms (one of them true and one false). In the group of patients with combination of abnormal ICA tortuosities and occlusions, there were areas and zones of cystic and glial abnormalities in 7, various degrees of small vessel disease and few liquor cysts in 18, and no abnormal brain matter foci in 6. No ICA malformations in combination with true or false aneurysms were found. The patients with combination of ICA malformations and stenosis, the signs of chronic brain ischemia were more advanced, compared to those in the patients with isolated ICA malformations (p=0.012). Conclusion : CT angiography is a highly informative method for the assessment of carotid arteries and brain matter in patients with ICA malformations. The combination with ICA malformations and occlusion is associated with more advanced lesions of brain matter." @default.
• W3134939064 created "2021-03-15" @default.
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• W3134939064 date "2021-03-30" @default.
• W3134939064 modified "2023-09-26" @default.
• W3134939064 title "Assessment of carotid arteries and brain matter in patients with isolated abnormal tortuosities and those combined with occlusion by computed tomography angiography" @default.
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• W3134939064 doi "https://doi.org/10.18786/2072-0505-2021-49-007" @default.
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