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- W3135236543 abstract "Adenovirus was originally used as a vector for gene therapy. In recent years, with the development of the next-generation vectors with increased safety and high immunogenicity to transgene products, its utility as a vaccine vector has continued to increase. Adenovirus-based vaccines are currently being tested not only to prevent various infectious diseases but also to be applied as cancer vaccines. In this review, I discuss the innate and adaptive aspects of the immunological characteristics of adenovirus vectors and further examine the current status of advanced adenovirus-based vaccine development. Various methods that can overcome the limitations of currently used adenoviruses as vaccine vehicles are also discussed. Through this study, I hope that vaccine development using adenovirus vectors will be expedited and more successful." @default.
- W3135236543 created "2021-03-15" @default.
- W3135236543 creator A5064273153 @default.
- W3135236543 date "2021-01-01" @default.
- W3135236543 modified "2023-10-11" @default.
- W3135236543 title "Adenovirus Vectors: Excellent Tools for Vaccine Development" @default.
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- W3135236543 doi "https://doi.org/10.4110/in.2021.21.e6" @default.
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