Matches in SemOpenAlex for { <https://semopenalex.org/work/W3135259744> ?p ?o ?g. }
- W3135259744 abstract "Abstract Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA has well established cardiovascular and neurocognitive sequelae, although the optimal metric to assess its severity and/or potential response to therapy remains unclear. The apnea-hypopnea index (AHI) is well established; thus, we review its history and predictive value in various different clinical contexts. Although the AHI is often criticized for its limitations, it remains the best studied metric of OSA severity, albeit imperfect. We further review the potential value of alternative metrics including hypoxic burden, arousal intensity, odds ratio product, and cardiopulmonary coupling. We conclude with possible future directions to capture clinically meaningful OSA endophenotypes including the use of genetics, blood biomarkers, machine/deep learning and wearable technologies. Further research in OSA should be directed towards providing diagnostic and prognostic information to make the OSA diagnosis more accessible and to improving prognostic information regarding OSA consequences, in order to guide patient care and to help in the design of future clinical trials." @default.
- W3135259744 created "2021-03-15" @default.
- W3135259744 creator A5001740246 @default.
- W3135259744 creator A5008797726 @default.
- W3135259744 creator A5011844829 @default.
- W3135259744 creator A5012820753 @default.
- W3135259744 creator A5037627845 @default.
- W3135259744 creator A5041913817 @default.
- W3135259744 creator A5047479450 @default.
- W3135259744 creator A5050535403 @default.
- W3135259744 creator A5064393146 @default.
- W3135259744 creator A5076513928 @default.
- W3135259744 creator A5091775732 @default.
- W3135259744 date "2021-03-09" @default.
- W3135259744 modified "2023-10-09" @default.
- W3135259744 title "Metrics of sleep apnea severity: beyond the apnea-hypopnea index" @default.
- W3135259744 cites W118211727 @default.
- W3135259744 cites W122529783 @default.
- W3135259744 cites W147768144 @default.
- W3135259744 cites W1492997461 @default.
- W3135259744 cites W1505973500 @default.
- W3135259744 cites W1545241942 @default.
- W3135259744 cites W1545509292 @default.
- W3135259744 cites W1554094632 @default.
- W3135259744 cites W1568045382 @default.
- W3135259744 cites W1582334813 @default.
- W3135259744 cites W1601575358 @default.
- W3135259744 cites W1603091860 @default.
- W3135259744 cites W1606927834 @default.
- W3135259744 cites W160785014 @default.
- W3135259744 cites W167576409 @default.
- W3135259744 cites W171305193 @default.
- W3135259744 cites W1823065994 @default.
- W3135259744 cites W1824133722 @default.
- W3135259744 cites W1837929068 @default.
- W3135259744 cites W188561823 @default.
- W3135259744 cites W1964924469 @default.
- W3135259744 cites W1964971416 @default.
- W3135259744 cites W1968771781 @default.
- W3135259744 cites W1970066295 @default.
- W3135259744 cites W1972002885 @default.
- W3135259744 cites W1972288936 @default.
- W3135259744 cites W1974032169 @default.
- W3135259744 cites W1975319022 @default.
- W3135259744 cites W1977620104 @default.
- W3135259744 cites W1979386519 @default.
- W3135259744 cites W1982822410 @default.
- W3135259744 cites W1983050487 @default.
- W3135259744 cites W1985360781 @default.
- W3135259744 cites W198820787 @default.
- W3135259744 cites W1988469351 @default.
- W3135259744 cites W1989619415 @default.
- W3135259744 cites W1990729619 @default.
- W3135259744 cites W1992241006 @default.
- W3135259744 cites W2003533532 @default.
- W3135259744 cites W2005417791 @default.
- W3135259744 cites W2007406952 @default.
- W3135259744 cites W2007885276 @default.
- W3135259744 cites W2011295831 @default.
- W3135259744 cites W2029520770 @default.
- W3135259744 cites W2030869203 @default.
- W3135259744 cites W2032617616 @default.
- W3135259744 cites W2034556696 @default.
- W3135259744 cites W2042412967 @default.
- W3135259744 cites W2042958005 @default.
- W3135259744 cites W2043086483 @default.
- W3135259744 cites W2050113062 @default.
- W3135259744 cites W2056110807 @default.
- W3135259744 cites W2063135200 @default.
- W3135259744 cites W2066596973 @default.
- W3135259744 cites W2069220162 @default.
- W3135259744 cites W2069340435 @default.
- W3135259744 cites W2071190468 @default.
- W3135259744 cites W2076918146 @default.
- W3135259744 cites W2079415435 @default.
- W3135259744 cites W2079485496 @default.
- W3135259744 cites W2083313958 @default.
- W3135259744 cites W2084877128 @default.
- W3135259744 cites W2085814883 @default.
- W3135259744 cites W2089335956 @default.
- W3135259744 cites W2092344206 @default.
- W3135259744 cites W2093372772 @default.
- W3135259744 cites W2095993223 @default.
- W3135259744 cites W2098077186 @default.
- W3135259744 cites W2098983190 @default.
- W3135259744 cites W2099608882 @default.
- W3135259744 cites W2103939721 @default.
- W3135259744 cites W2106541217 @default.
- W3135259744 cites W2106908605 @default.
- W3135259744 cites W2109017678 @default.
- W3135259744 cites W2114942155 @default.
- W3135259744 cites W2117075490 @default.
- W3135259744 cites W2117834225 @default.
- W3135259744 cites W2119063805 @default.
- W3135259744 cites W2119213758 @default.
- W3135259744 cites W2120788437 @default.
- W3135259744 cites W2122295507 @default.
- W3135259744 cites W2126107107 @default.
- W3135259744 cites W2127030366 @default.
- W3135259744 cites W2128416574 @default.