Matches in SemOpenAlex for { <https://semopenalex.org/work/W3135292808> ?p ?o ?g. }
- W3135292808 endingPage "1438" @default.
- W3135292808 startingPage "1438" @default.
- W3135292808 abstract "This article presents the evaluation of diblock and triblock poly(ethylene glycol)-b-poly(1,3-trimethylene carbonate) amphiphilic copolymers (PEG-PTMCs) as excipients for the formulation of long-acting injectables (LAIs). Copolymers were successfully synthesised through bulk ring-opening polymerisation. The concomitant formation of PTMC homopolymer could not be avoided irrespective of the catalyst amount, but the by-product could easily be removed by gel chromatography. Pure PEG-PTMCs undergo faster erosion in vivo than their corresponding homopolymer. Furthermore, these copolymers show outstanding stability compared to their polyester analogues when formulated with amine-containing reactive drugs, which makes them particularly suitable as LAIs for the sustained release of drugs susceptible to acylation." @default.
- W3135292808 created "2021-03-15" @default.
- W3135292808 creator A5014335497 @default.
- W3135292808 creator A5024068592 @default.
- W3135292808 creator A5030615371 @default.
- W3135292808 creator A5032285138 @default.
- W3135292808 creator A5088545589 @default.
- W3135292808 date "2021-03-06" @default.
- W3135292808 modified "2023-10-16" @default.
- W3135292808 title "Poly(ethylene glycol)-b-poly(1,3-trimethylene carbonate) Amphiphilic Copolymers for Long-Acting Injectables: Synthesis, Non-Acylating Performance and In Vivo Degradation" @default.
- W3135292808 cites W1547361471 @default.
- W3135292808 cites W1561502224 @default.
- W3135292808 cites W1875751133 @default.
- W3135292808 cites W1974371653 @default.
- W3135292808 cites W1976075691 @default.
- W3135292808 cites W1980157820 @default.
- W3135292808 cites W1981452990 @default.
- W3135292808 cites W1982222817 @default.
- W3135292808 cites W2002107034 @default.
- W3135292808 cites W2009395935 @default.
- W3135292808 cites W2016607969 @default.
- W3135292808 cites W2024647894 @default.
- W3135292808 cites W2047584199 @default.
- W3135292808 cites W2054821145 @default.
- W3135292808 cites W2057051140 @default.
- W3135292808 cites W2057697685 @default.
- W3135292808 cites W2060824783 @default.
- W3135292808 cites W2063314046 @default.
- W3135292808 cites W2069318561 @default.
- W3135292808 cites W2077506251 @default.
- W3135292808 cites W2091155912 @default.
- W3135292808 cites W2095313483 @default.
- W3135292808 cites W2099384439 @default.
- W3135292808 cites W2101113782 @default.
- W3135292808 cites W2119083444 @default.
- W3135292808 cites W2131130895 @default.
- W3135292808 cites W2135880302 @default.
- W3135292808 cites W2139956440 @default.
- W3135292808 cites W2150318390 @default.
- W3135292808 cites W2150605423 @default.
- W3135292808 cites W2160277604 @default.
- W3135292808 cites W2171428511 @default.
- W3135292808 cites W2217671214 @default.
- W3135292808 cites W2260094026 @default.
- W3135292808 cites W2330380201 @default.
- W3135292808 cites W2413905853 @default.
- W3135292808 cites W2556103485 @default.
- W3135292808 cites W2767489314 @default.
- W3135292808 cites W2787136753 @default.
- W3135292808 cites W2943940643 @default.
- W3135292808 cites W2976818637 @default.
- W3135292808 cites W2996165605 @default.
- W3135292808 cites W2998897220 @default.
- W3135292808 cites W3016205181 @default.
- W3135292808 cites W3158059237 @default.
- W3135292808 cites W4250766053 @default.
- W3135292808 doi "https://doi.org/10.3390/molecules26051438" @default.
- W3135292808 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7962012" @default.
- W3135292808 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33800940" @default.
- W3135292808 hasPublicationYear "2021" @default.
- W3135292808 type Work @default.
- W3135292808 sameAs 3135292808 @default.
- W3135292808 citedByCount "2" @default.
- W3135292808 countsByYear W31352928082021 @default.
- W3135292808 countsByYear W31352928082023 @default.
- W3135292808 crossrefType "journal-article" @default.
- W3135292808 hasAuthorship W3135292808A5014335497 @default.
- W3135292808 hasAuthorship W3135292808A5024068592 @default.
- W3135292808 hasAuthorship W3135292808A5030615371 @default.
- W3135292808 hasAuthorship W3135292808A5032285138 @default.
- W3135292808 hasAuthorship W3135292808A5088545589 @default.
- W3135292808 hasBestOaLocation W31352928081 @default.
- W3135292808 hasConcept C10138342 @default.
- W3135292808 hasConcept C119394753 @default.
- W3135292808 hasConcept C15920480 @default.
- W3135292808 hasConcept C161790260 @default.
- W3135292808 hasConcept C162324750 @default.
- W3135292808 hasConcept C178790620 @default.
- W3135292808 hasConcept C185592680 @default.
- W3135292808 hasConcept C188027245 @default.
- W3135292808 hasConcept C192562407 @default.
- W3135292808 hasConcept C193557335 @default.
- W3135292808 hasConcept C203897987 @default.
- W3135292808 hasConcept C2777516009 @default.
- W3135292808 hasConcept C2781042915 @default.
- W3135292808 hasConcept C44228677 @default.
- W3135292808 hasConcept C521977710 @default.
- W3135292808 hasConcept C54400483 @default.
- W3135292808 hasConcept C67407626 @default.
- W3135292808 hasConceptScore W3135292808C10138342 @default.
- W3135292808 hasConceptScore W3135292808C119394753 @default.
- W3135292808 hasConceptScore W3135292808C15920480 @default.
- W3135292808 hasConceptScore W3135292808C161790260 @default.
- W3135292808 hasConceptScore W3135292808C162324750 @default.
- W3135292808 hasConceptScore W3135292808C178790620 @default.
- W3135292808 hasConceptScore W3135292808C185592680 @default.
- W3135292808 hasConceptScore W3135292808C188027245 @default.
- W3135292808 hasConceptScore W3135292808C192562407 @default.