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- W3135353438 abstract "This study examined the in vitro activity of iclaprim and comparators against 40 Listeria monocytogenes clinical isolates mostly (95%) from patients with bloodstream infection (BSI) from the USA, Australia/New Zealand, Latin America and Europe collected between 2012–2018. Antimicrobial susceptibility testing was performed according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Minimum inhibitory concentration (MIC) interpretations were based on CLSI criteria. The iclaprim MIC90 value for all L. monocytogenes was 0.015 μg/mL. The MIC50/90 values for iclaprim were 4-fold lower than trimethoprim, the only FDA-approved dihydrofolate reductase inhibitor, against all L. monocytogenes. Iclaprim demonstrated lower MIC values than trimethoprim against a collection (2012–2018) of L. monocytogenes clinical isolates mostly from patients with BSI from the USA, Australia/New Zealand, Latin America and Europe." @default.
- W3135353438 created "2021-03-15" @default.
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- W3135353438 date "2021-06-01" @default.
- W3135353438 modified "2023-09-26" @default.
- W3135353438 title "In vitro activity of iclaprim and comparator agents against Listeria monocytogenes clinical isolates from 2012 to 2018" @default.
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- W3135353438 doi "https://doi.org/10.1016/j.jgar.2021.02.015" @default.
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