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W3135389098 abstract "Data on fertility after autologous hematopoietic stem cell transplantation (aHSCT) in women with multiple sclerosis (MS) are inconclusive. This study aims to report on post-aHSCT menstrual resumption in a multi-center MS-women cohort. Out of 43 women, 30 (70%) recovered menses after a mean time of 6.8 months. Older age (odds ratio (OR) = 0.5, p < 0.0001) and previous pulsed cyclophosphamide (OR = 0.44, p = 0.005) were independently associated with a reduced menstrual recovery probability. Conditioning regimens' intensity resulted not associated with post-procedure amenorrhea. Our results highlight younger age as significantly associated with menses recovery; proper fertility counseling for MS women candidated to aHSCT both prior- and post-transplantation is therefore warranted." @default.
W3135389098 created "2021-03-15" @default.
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W3135389098 date "2021-03-12" @default.
W3135389098 modified "2023-10-17" @default.
W3135389098 title "Menstrual cycle resumption and female fertility after autologous hematopoietic stem cell transplantation for multiple sclerosis" @default.
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W3135389098 doi "https://doi.org/10.1177/13524585211000616" @default.
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