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- W3135521758 abstract "Metabolite-enabled killing of antibiotic-resistant pathogens by antibiotics is an attractive strategy to manage antibiotic resistance. Our previous study demonstrated that alanine or/and glucose increased the killing efficacy of kanamycin on antibiotic-resistant bacteria, whose action is through up-regulating TCA cycle, increasing proton motive force and enhancing antibiotic uptake. Despite the fact that alanine altered several metabolic pathways, other mechanisms could be potentially involved in alanine-mediated kanamycin killing of bacteria which remains to be explored. In the present study, we adopted proteomic approach to analyze the proteome changes induced by exogenous alanine." @default.
- W3135521758 created "2021-03-15" @default.
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- W3135521758 date "2020-01-01" @default.
- W3135521758 modified "2023-09-26" @default.
- W3135521758 title "Alanine Enhances Aminoglycosides-Induced ROS Production by Metabolic Regulation" @default.
- W3135521758 hasPublicationYear "2020" @default.
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