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• W3135702308 abstract "Conocer el perfil sociodemográfico y clínico en una muestra representativa de personas con diabetes mellitus tipo 1 (DM1) en España, e identificar los factores asociados con el control glucémico. Estudio observacional, transversal en adultos y niños con DM1 tratados en las consultas de 75 hospitales públicos españoles, distribuidos geográficamente para ser representativos de la población española. Dentro de cada centro, los pacientes fueron incluidos de forma consecutiva según acudían a consulta. Se les entrevistó y se revisaron sus historias clínicas. Se realizó un análisis estadístico descriptivo y se analizaron los factores asociados con la hemoglobina glicada (HbA 1c ) utilizando un análisis de regresión lineal multivariante. Se incluyeron 647 pacientes: 55,3% mujeres, edad 36,6 ± 14,4 años, 97,2% caucásicos, índice de masa corporal (IMC) 24,7 ± 4,4 kg/m 2 (12,1% ≥ 30 kg/m 2 ) y el 74,0% tenía estudios secundarios/universitarios. El 20,2% eran fumadores activos. El tiempo medio desde el diagnóstico de DM1 fue de 17,9 ± 12,0 años. Un 48,7% presentaban comorbilidades, un 19,3% retinopatía y un 16,4% hipotiroidismo. Respecto al tratamiento para la DM1, el 76,5% usaban insulinoterapia basal-bolo y el 20,7% infusión subcutánea continua de insulina (ISCI); el 51,0% de los pacientes utilizaban una ratio insulina/hidratos de carbono (ICR), realizaban 4,6 ± 1,6 autoanálisis de glucemia capilar (AAGC) diaria y el 24,8% utilizaba monitorización continua de glucosa (MCG). El valor medio de la HbA 1c fue del 7,6 ± 1,1% (30% inferior al 7%). El control metabólico fue mejor (menor HbA 1c ) a mayor número de AAGC diarios (B = −0,053; p = 0,009), mayor nivel de estudios (B = 0,461; p < 0,001), mayor número de hipoglucemias (B = −0,253; p = 0,018) y la realización de recuento de hidratos de carbono (B = −0,190; p = 0,048), y peor a mayor duración de la enfermedad (B = 0,010; p = 0,010), mayor dosis total de insulina (B = 0,010; p < 0,0001), peor adherencia a la dieta (B = 0,650; p < 0,0001) y con antecedentes familiares de DM (B = −0,233; p = 0,007). El manejo de los pacientes con DM1 en España, así como el tratamiento que reciben, es similar al observado en otros países occidentales. El control glucémico está asociado al nivel de estudios, la duración de la enfermedad y las características del tratamiento y autocuidado. To determine the sociodemographic and clinical profile of a representative sample of people with type 1 diabetes mellitus (DM1) in Spain and identify factors associated with glycemic control. A cross-sectional observational study was carried out in adults and children with DM1 treated in 75 Spanish public hospitals, geographically distributed in order to be representative of the Spanish population. Within each center, the patients were included on a consecutive basis as they visited the clinic. They were interviewed, and their clinical histories were reviewed. A descriptive statistical analysis was made, and factors associated with HbA 1c were analyzed using multivariate linear regression analysis. A total of 647 patients were included: 55.3% females, aged 36.6 ± 14.4 years, 97.2% Caucasians, BMI 24.7 ± 4.4 kg/m 2 (12.1% ≥30 kg/m 2 ), and 74.0% had secondary / university education. A total of 20.2% were active smokers. The mean time from the diagnosis of DM1 was 17.9 ± 12.0 years. A total of 48.7% presented comorbidities: 19.3% retinopathy and 16.4% hypothyroidism. As regards treatment for DM1, 76.5% received basal-bolus insulin therapy and 20.7% continuous subcutaneous insulin infusion (CSII); 51.0% of the patients used an insulin/carbohydrate ratio (ICR), with 4.6 ± 1.6 self-monitored capillary blood glucose (SMCBG) measurements a day, and 24.8% used continuous glucose monitoring (CGM). The mean HbA 1c value was 7.6 ± 1.1% (30% below 7%). Metabolic control improved (lower HbA 1c ) with more daily SMCBG (B=−0.053; p=0.009), a higher educational level (B=0.461; P <0.001), greater number of hypoglycemia episodes (B=−0.253; P =0.018) and carbohydrate counting (B=−0.190; P =0.048), and worsened the longer the duration of the disease (B=0.010; P =0.010), higher total dose of insulin (B=0.010; P <0.0001), poorer adherence to diet (B=0.650; P <0.0001) and a family history of DM (B=−0.233; P =0.007). The management of patients with DM1 in Spain, as well as the treatment they receive, is similar to that seen in other Western countries. Blood glucose control is associated with educational level, disease duration, and the characteristics of treatment and self-care." @default.
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• W3135702308 date "2021-11-01" @default.
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• W3135702308 title "Características clínicas y manejo de la diabetes tipo 1 en España. Estudio SED1" @default.
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