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- W3135732595 abstract "Glycopolymers are polymers with pendant saccharides that are known to exhibit special properties of molecular recognition due to their unique physical properties. Glycopolymers are interesting materials on their own, but conjugating them with other molecules gives them different possibilities and applications. Applications in cell culture, biosensors, and glycan arrays have been reported using glycopolymer conjugates with solid substrates. Glycopolymer-conjugated nanoparticles, including gold nanoparticles, quantum dots, and magnetic particles, have been used in biosensing, bioimaging, and bioseparation, based on the molecular recognition ability of glycopolymers, combined with the optical, electronic, and magnetic functions of nanoparticles. Glycopolymer conjugates with proteins and cells exhibit new functionality, such as increased thermal stability and more potent immune responses of protein conjugates, and altered cell differentiation in cell conjugates. Since glycopolymers are water-soluble and amphiphilic polymers, solubilization of nanocarbons and coating of polymers on solid substrates have been achieved by conjugation with glycopolymers. In the preparation of glycopolymer conjugates, living radical polymerizations such as atom transfer radical polymerization (ATRP) and reversible addition-fragmentation chain transfer (RAFT) are useful methods that have been comprehensively described. The copolymerization of glycopolymers with other functional monomers such as the trimethoxy silyl group and dopamine units is also advantageous. Conjugation of glycopolymers to various molecular families is an interesting method for expanding the functions of saccharides and may lead to useful biological applications." @default.
- W3135732595 created "2021-03-15" @default.
- W3135732595 creator A5061667335 @default.
- W3135732595 date "2021-01-01" @default.
- W3135732595 modified "2023-10-16" @default.
- W3135732595 title "Glycopolymer Conjugates: Preparation and Functions" @default.
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