FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3135759675> ?p ?o ?g. }

• W3135759675 endingPage "5709" @default.
• W3135759675 startingPage "5701" @default.
• W3135759675 abstract "To discuss the role of benzydamine in the prevention and treatment of radiation-induced oral mucositis (OM) in head and neck (H&N) cancer patients. This document represents an expert opinion paper on indications and key-role aspects in OM pathogenesis, prevention and treatment.OM represents a common side effect of chemotherapy (CHT) and radiotherapy (RT). It consists in a painful erythema involving the oral cavity mucosa, which may progress to ulceration. Five biologically dynamic phases are considered crucial in mucositis: initiation, signalling, amplification, ulceration and healing. Oral environment and microbiota are fundamental in mucositis development being involved in susceptibility to infections and in ulceration consequences. Different agents against mucositis have been studied and the use of benzydamine is strongly supported in literature. The Multinational Association of Supportive Care in Cancer and International Society for Oral Oncology (MASCC/ISOO) guidelines recommend its use for the prevention of OM in H&N patients undergoing RT and RT/CHT.Benzydamine is a local anti-inflammatory drug with analgesic properties. It can decrease TNF-α, IL-1β and prostaglandin synthesis, also inhibiting leukocyte-endothelial interactions, neutrophil degranulation, vasodilation and vascular permeability. Literature agrees on the beneficial effects of benzydamine in preventing and reducing oral mucositis severity in H&N cancer patients undergoing RT/CHT.Mucositis represents a major concern in H&N cancer patients and a clinical and economical issue. A multimodal and multidisciplinary approach is needed for its management. International guidelines recommend benzydamine for OM prevention and treatment in H&N cancer patients, but further real world trials should be designed." @default.
• W3135759675 created "2021-03-15" @default.
• W3135759675 creator A5018624121 @default.
• W3135759675 creator A5043068937 @default.
• W3135759675 creator A5046156308 @default.
• W3135759675 creator A5081945327 @default.
• W3135759675 date "2021-03-01" @default.
• W3135759675 modified "2023-10-16" @default.
• W3135759675 title "The role of benzydamine in prevention and treatment of chemoradiotherapy-induced mucositis" @default.
• W3135759675 cites W1588772002 @default.
• W3135759675 cites W1905533598 @default.
• W3135759675 cites W1918425272 @default.
• W3135759675 cites W1966996796 @default.
• W3135759675 cites W1967208836 @default.
• W3135759675 cites W1976971060 @default.
• W3135759675 cites W1978519654 @default.
• W3135759675 cites W1992895388 @default.
• W3135759675 cites W1997571796 @default.
• W3135759675 cites W2005514220 @default.
• W3135759675 cites W2007615256 @default.
• W3135759675 cites W2009816300 @default.
• W3135759675 cites W2019459387 @default.
• W3135759675 cites W2022453432 @default.
• W3135759675 cites W2049862610 @default.
• W3135759675 cites W2066853142 @default.
• W3135759675 cites W2071748263 @default.
• W3135759675 cites W2073348610 @default.
• W3135759675 cites W2090018471 @default.
• W3135759675 cites W2099955626 @default.
• W3135759675 cites W2111642144 @default.
• W3135759675 cites W2121481925 @default.
• W3135759675 cites W2129040422 @default.
• W3135759675 cites W2145063848 @default.
• W3135759675 cites W2155534668 @default.
• W3135759675 cites W2158334747 @default.
• W3135759675 cites W2163437833 @default.
• W3135759675 cites W2163643208 @default.
• W3135759675 cites W2164520360 @default.
• W3135759675 cites W2285817164 @default.
• W3135759675 cites W2511177500 @default.
• W3135759675 cites W2567252353 @default.
• W3135759675 cites W2586127268 @default.
• W3135759675 cites W2751128104 @default.
• W3135759675 cites W2803047937 @default.
• W3135759675 cites W2897373621 @default.
• W3135759675 cites W2956663376 @default.
• W3135759675 cites W2956682361 @default.
• W3135759675 cites W2957093927 @default.
• W3135759675 cites W2957136025 @default.
• W3135759675 cites W2958929637 @default.
• W3135759675 cites W2981375681 @default.
• W3135759675 cites W2987771176 @default.
• W3135759675 cites W3190697283 @default.
• W3135759675 cites W325430807 @default.
• W3135759675 doi "https://doi.org/10.1007/s00520-021-06048-5" @default.
• W3135759675 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8410701" @default.
• W3135759675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33649918" @default.
• W3135759675 hasPublicationYear "2021" @default.
• W3135759675 type Work @default.
• W3135759675 sameAs 3135759675 @default.
• W3135759675 citedByCount "17" @default.
• W3135759675 countsByYear W31357596752021 @default.
• W3135759675 countsByYear W31357596752022 @default.
• W3135759675 countsByYear W31357596752023 @default.
• W3135759675 crossrefType "journal-article" @default.
• W3135759675 hasAuthorship W3135759675A5018624121 @default.
• W3135759675 hasAuthorship W3135759675A5043068937 @default.
• W3135759675 hasAuthorship W3135759675A5046156308 @default.
• W3135759675 hasAuthorship W3135759675A5081945327 @default.
• W3135759675 hasBestOaLocation W31357596751 @default.
• W3135759675 hasConcept C121608353 @default.
• W3135759675 hasConcept C126322002 @default.
• W3135759675 hasConcept C143998085 @default.
• W3135759675 hasConcept C177713679 @default.
• W3135759675 hasConcept C2776530083 @default.
• W3135759675 hasConcept C2778496288 @default.
• W3135759675 hasConcept C509974204 @default.
• W3135759675 hasConcept C71924100 @default.
• W3135759675 hasConcept C90924648 @default.
• W3135759675 hasConceptScore W3135759675C121608353 @default.
• W3135759675 hasConceptScore W3135759675C126322002 @default.
• W3135759675 hasConceptScore W3135759675C143998085 @default.
• W3135759675 hasConceptScore W3135759675C177713679 @default.
• W3135759675 hasConceptScore W3135759675C2776530083 @default.
• W3135759675 hasConceptScore W3135759675C2778496288 @default.
• W3135759675 hasConceptScore W3135759675C509974204 @default.
• W3135759675 hasConceptScore W3135759675C71924100 @default.
• W3135759675 hasConceptScore W3135759675C90924648 @default.
• W3135759675 hasFunder F4320323946 @default.
• W3135759675 hasIssue "10" @default.
• W3135759675 hasLocation W31357596751 @default.
• W3135759675 hasLocation W31357596752 @default.
• W3135759675 hasLocation W31357596753 @default.
• W3135759675 hasLocation W31357596754 @default.
• W3135759675 hasLocation W31357596755 @default.
• W3135759675 hasOpenAccess W3135759675 @default.
• W3135759675 hasPrimaryLocation W31357596751 @default.
• W3135759675 hasRelatedWork W2132010426 @default.

• next