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- W3135800441 abstract "Background: Platelets play a key role in the development and progression ofcardiovascular diseases. Also red cell distribution width (RDW%) & plateletindices are a good predictor of clinical outcomes. Purpose: Study the relationship between RDW%, platelets count, mean plateletvolume (MPVfl) and platelet distribution width (PDWfl) in children withcongenital heart disease (CHD) or rheumaticheart diseases (RHD). Subjects and Methods: The studywas carried on 151 children diagnosed as CHD or RHD selected from pediatricdepartment of Al-Zahraa University Hospital and National Heart Institute. They were aged from 6 months to 12 years.Another 80 apparently healthy children were taken as controls. Completeblood count and echocardiography examination were evaluated for allparticipants. Results: The mean value of RDW% was increasedin CHD and RHD than controls, RDW% higher in cyanotic CHD (CCHD) (eitherdecompensated or compensated) than acyanotic CHD, and in decompensated RHD thancompensated RHD with more than one valve affection. The mean platelets countwere decreased in cyanotic than acyanotic CHD, platelets count were increasedin decompensated than compensated RHD eitherwith one valve or more than one valve affection. The mean values of MPVand PDW were increased in decompensated CHD, but it decreased in decompensatedRHD. Conclusion: The RDW%, MPV and PDW considered as simple markers inthe follow up of patients with CHD or RHD for early detection of seriouscomplication." @default.
- W3135800441 created "2021-03-15" @default.
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- W3135800441 date "2021-01-01" @default.
- W3135800441 modified "2023-09-26" @default.
- W3135800441 title "Evaluation of Red Cell Distribution Width and Platelet Indices in Children with Chronic Heart Disease" @default.
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- W3135800441 doi "https://doi.org/10.4236/ojped.2021.111008" @default.
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