FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3135844655> ?p ?o ?g. }

• W3135844655 abstract "Severe acute respiratory syndrome SARS-CoV-2 has caused a global pandemic starting in 2020. Accordingly, testing is crucial for mitigating the economic and public health effects. In order to facilitate point-of-care diagnosis, this study aims at presenting a label-free electrochemical biosensor as a powerful nanobiodevice for SARS-CoV-2 spike protein detection. Utilizing the IgG anti-SARS-CoV-2 spike antibody onto the electrode surface as a specific platform in an ordered orientation through staphylococcal protein A (ProtA) is highly significant in fabricating the designed nanobiodevice. In this sense, the screen-printed carbon electrode modified with Cu2O nanocubes (Cu2O NCs), which provide a large surface area in a very small space, was applied in order to increase the ProtA loading on the electrode surface. Accordingly, the sensitivity and stability of the sensing platform significantly increased. The electrochemical evaluations proved that there is a very good linear relationship between the charge transfer resistance (Rct) and spike protein contents via a specific binding reaction in the range 0.25 fg mL-1 to 1 μg mL-1. Moreover, the assay when tested with influenza viruses 1 and 2 was performed in 20 min with a low detection limit of 0.04 fg mL-1 for spike protein without any cross-reactivity. The designed nanobiodevice exhibited an average satisfactory recovery rate of ~ 97-103% in different artificial sample matrices, i.e., saliva, artificial nasal, and universal transport medium (UTM), illustrating its high detection performance and practicability. The nanobiodevice was also tested using real patients and healthy samples, where the results had been already obtained using the standard polymerase chain reaction (PCR) procedure, and showed satisfactory results. Graphical abstract." @default.
• W3135844655 created "2021-03-15" @default.
• W3135844655 creator A5012772114 @default.
• W3135844655 creator A5031999726 @default.
• W3135844655 creator A5058415666 @default.
• W3135844655 creator A5075535050 @default.
• W3135844655 date "2021-03-01" @default.
• W3135844655 modified "2023-09-30" @default.
• W3135844655 title "Electrochemical immunosensor with Cu2O nanocube coating for detection of SARS-CoV-2 spike protein" @default.
• W3135844655 cites W1517481555 @default.
• W3135844655 cites W1970624085 @default.
• W3135844655 cites W1983962835 @default.
• W3135844655 cites W1992512785 @default.
• W3135844655 cites W1994958801 @default.
• W3135844655 cites W2018260743 @default.
• W3135844655 cites W2060957841 @default.
• W3135844655 cites W2083484452 @default.
• W3135844655 cites W2085302056 @default.
• W3135844655 cites W2087855250 @default.
• W3135844655 cites W2526509292 @default.
• W3135844655 cites W2526737293 @default.
• W3135844655 cites W2790429379 @default.
• W3135844655 cites W2922060538 @default.
• W3135844655 cites W2953930626 @default.
• W3135844655 cites W2969762541 @default.
• W3135844655 cites W2999753256 @default.
• W3135844655 cites W3003637715 @default.
• W3135844655 cites W3008090866 @default.
• W3135844655 cites W3008818676 @default.
• W3135844655 cites W3008928028 @default.
• W3135844655 cites W3009219040 @default.
• W3135844655 cites W3010065407 @default.
• W3135844655 cites W3011839959 @default.
• W3135844655 cites W3015636815 @default.
• W3135844655 cites W3021601129 @default.
• W3135844655 cites W3023276205 @default.
• W3135844655 cites W3034803357 @default.
• W3135844655 cites W3038099076 @default.
• W3135844655 cites W3043115209 @default.
• W3135844655 cites W3083182349 @default.
• W3135844655 cites W3086049344 @default.
• W3135844655 cites W3087003711 @default.
• W3135844655 cites W3089965698 @default.
• W3135844655 cites W3092145882 @default.
• W3135844655 cites W3093451772 @default.
• W3135844655 cites W3096643716 @default.
• W3135844655 cites W3106157958 @default.
• W3135844655 cites W562792646 @default.
• W3135844655 doi "https://doi.org/10.1007/s00604-021-04762-9" @default.
• W3135844655 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7921825" @default.
• W3135844655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33651173" @default.
• W3135844655 hasPublicationYear "2021" @default.
• W3135844655 type Work @default.
• W3135844655 sameAs 3135844655 @default.
• W3135844655 citedByCount "90" @default.
• W3135844655 countsByYear W31358446552021 @default.
• W3135844655 countsByYear W31358446552022 @default.
• W3135844655 countsByYear W31358446552023 @default.
• W3135844655 crossrefType "journal-article" @default.
• W3135844655 hasAuthorship W3135844655A5012772114 @default.
• W3135844655 hasAuthorship W3135844655A5031999726 @default.
• W3135844655 hasAuthorship W3135844655A5058415666 @default.
• W3135844655 hasAuthorship W3135844655A5075535050 @default.
• W3135844655 hasBestOaLocation W31358446551 @default.
• W3135844655 hasConcept C10349863 @default.
• W3135844655 hasConcept C119128265 @default.
• W3135844655 hasConcept C142724271 @default.
• W3135844655 hasConcept C147789679 @default.
• W3135844655 hasConcept C160756335 @default.
• W3135844655 hasConcept C171250308 @default.
• W3135844655 hasConcept C17525397 @default.
• W3135844655 hasConcept C180238147 @default.
• W3135844655 hasConcept C185592680 @default.
• W3135844655 hasConcept C192562407 @default.
• W3135844655 hasConcept C2779134260 @default.
• W3135844655 hasConcept C2781448156 @default.
• W3135844655 hasConcept C2909509916 @default.
• W3135844655 hasConcept C3008058167 @default.
• W3135844655 hasConcept C43617362 @default.
• W3135844655 hasConcept C524204448 @default.
• W3135844655 hasConcept C52859227 @default.
• W3135844655 hasConcept C71924100 @default.
• W3135844655 hasConceptScore W3135844655C10349863 @default.
• W3135844655 hasConceptScore W3135844655C119128265 @default.
• W3135844655 hasConceptScore W3135844655C142724271 @default.
• W3135844655 hasConceptScore W3135844655C147789679 @default.
• W3135844655 hasConceptScore W3135844655C160756335 @default.
• W3135844655 hasConceptScore W3135844655C171250308 @default.
• W3135844655 hasConceptScore W3135844655C17525397 @default.
• W3135844655 hasConceptScore W3135844655C180238147 @default.
• W3135844655 hasConceptScore W3135844655C185592680 @default.
• W3135844655 hasConceptScore W3135844655C192562407 @default.
• W3135844655 hasConceptScore W3135844655C2779134260 @default.
• W3135844655 hasConceptScore W3135844655C2781448156 @default.
• W3135844655 hasConceptScore W3135844655C2909509916 @default.
• W3135844655 hasConceptScore W3135844655C3008058167 @default.
• W3135844655 hasConceptScore W3135844655C43617362 @default.
• W3135844655 hasConceptScore W3135844655C524204448 @default.
• W3135844655 hasConceptScore W3135844655C52859227 @default.
• W3135844655 hasConceptScore W3135844655C71924100 @default.

• next