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- W3135938859 abstract "Compounds bearing fluorinated moieties are pervasive in a wide range of pharmaceuticals and agrochemicals. The installation of fluorinated units is a persistently vital task in synthetic chemistry, where facile and manipulable assays are highly demanding. Herein, we establish a general and programmable fluorination strategy for the modular assembly of mono- and difluoromethylarenes through the controllable deprotonation and fluorination of phosphonium ylides. Moreover, the rational combination of the reaction sequence allows the rapid construction of diversified fluorine-containing arenes." @default.
- W3135938859 created "2021-03-29" @default.
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- W3135938859 date "2021-03-19" @default.
- W3135938859 modified "2023-10-14" @default.
- W3135938859 title "Phosphonium Ylide-Mediated Programmable Fluorination to Access Mono- and Difluoromethylarenes" @default.
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- W3135938859 doi "https://doi.org/10.1021/acs.orglett.1c00457" @default.
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