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• W3136084792 endingPage "107842" @default.
• W3136084792 startingPage "107842" @default.
• W3136084792 abstract "At present most of the evidence for the relevance of oligomerization for the pharmacology of depression comes from in vitro studies which identified oligomers, and from neuropsychopharmacological studies of receptors which participate in oligomerization. For example, behavioural and biochemical studies in knockout animals suggest that GPR39 may mediate the antidepressant action of monoaminergic antidepressants. We have recently found long-lasting antidepressant-like effects of GPR39 agonist, thus suggesting GPR39 as a target for the development of novel antidepressant drugs. In vitro studies have shown that GPR39 oligomerizes with other GPCRs. Oligomerization of GPR39 should thus be considered in relation to the development of new antidepressants targeting this receptor as well as antidepressants targeting other receptors that may form complexes with GPR39. Here, we summarize recent data suggestive of the importance of oligomerization for the pharmacology of depression and discuss approaches for validation of this phenomenon." @default.
• W3136084792 created "2021-03-29" @default.
• W3136084792 creator A5019754051 @default.
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• W3136084792 creator A5083461425 @default.
• W3136084792 date "2021-09-01" @default.
• W3136084792 modified "2023-09-30" @default.
• W3136084792 title "GPCR oligomerization as a target for antidepressants: Focus on GPR39" @default.
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• W3136084792 cites W1570450680 @default.
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• W3136084792 cites W1969431118 @default.
• W3136084792 cites W1973309926 @default.
• W3136084792 cites W1974782466 @default.
• W3136084792 cites W1976347725 @default.
• W3136084792 cites W1978696776 @default.
• W3136084792 cites W1998966506 @default.
• W3136084792 cites W2002235118 @default.
• W3136084792 cites W2006751457 @default.
• W3136084792 cites W2010054737 @default.
• W3136084792 cites W2011680648 @default.
• W3136084792 cites W2014373387 @default.
• W3136084792 cites W2020152715 @default.
• W3136084792 cites W2026920991 @default.
• W3136084792 cites W2053127867 @default.
• W3136084792 cites W2059585701 @default.
• W3136084792 cites W2064715357 @default.
• W3136084792 cites W2069300470 @default.
• W3136084792 cites W2080797234 @default.
• W3136084792 cites W2084809614 @default.
• W3136084792 cites W2085462740 @default.
• W3136084792 cites W2086726646 @default.
• W3136084792 cites W2086889423 @default.
• W3136084792 cites W2087936498 @default.
• W3136084792 cites W2087978290 @default.
• W3136084792 cites W2091064555 @default.
• W3136084792 cites W2092859157 @default.
• W3136084792 cites W2092956762 @default.
• W3136084792 cites W2100445528 @default.
• W3136084792 cites W2109014958 @default.
• W3136084792 cites W2110469184 @default.
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• W3136084792 cites W2118163991 @default.
• W3136084792 cites W2118710970 @default.
• W3136084792 cites W2120538193 @default.
• W3136084792 cites W2121105777 @default.
• W3136084792 cites W2150092716 @default.
• W3136084792 cites W2155071292 @default.
• W3136084792 cites W2161207949 @default.
• W3136084792 cites W218056410 @default.
• W3136084792 cites W2183216728 @default.
• W3136084792 cites W2266322781 @default.
• W3136084792 cites W2293846056 @default.
• W3136084792 cites W2316662834 @default.
• W3136084792 cites W2397491710 @default.
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• W3136084792 cites W2560018081 @default.
• W3136084792 cites W2585390649 @default.
• W3136084792 cites W2588290172 @default.
• W3136084792 cites W2748742210 @default.
• W3136084792 cites W2760890203 @default.
• W3136084792 cites W2765153686 @default.
• W3136084792 cites W2768264471 @default.
• W3136084792 cites W2774455409 @default.
• W3136084792 cites W2775795535 @default.
• W3136084792 cites W2780149280 @default.
• W3136084792 cites W2782382515 @default.
• W3136084792 cites W2789872730 @default.
• W3136084792 cites W2790485737 @default.
• W3136084792 cites W2895708131 @default.
• W3136084792 cites W2898699929 @default.
• W3136084792 cites W2899496984 @default.
• W3136084792 cites W2900682399 @default.
• W3136084792 cites W2913330066 @default.
• W3136084792 cites W2943639494 @default.
• W3136084792 cites W2948641599 @default.
• W3136084792 cites W2978956383 @default.
• W3136084792 cites W2980504460 @default.
• W3136084792 cites W2987429439 @default.
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• W3136084792 cites W3013824813 @default.
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• W3136084792 doi "https://doi.org/10.1016/j.pharmthera.2021.107842" @default.
• W3136084792 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33746052" @default.
• W3136084792 hasPublicationYear "2021" @default.
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