FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136086176> ?p ?o ?g. }

• W3136086176 abstract "Abstract Background: Neonatal sepsis is a systemic inflammatory response syndrome in neonates. The molecular mechanism of neonatal sepsis remains incompletely clarified. The purpose of this study was to explore the potential value of receptor interacting protein 3 (RIP3) in neonatal sepsis. Methods: 93 neonates with sepsis and 93 neonates without infectious diseases were enrolled in this study from September 2019 to March 2021. Plasma RIP3 was detected by enzyme-linked immunosorbent assay (ELISA) and assessed along with whole blood hypersensitive C-reactive protein (hs-CRP) and platelet count (PLT). Differences of RIP3, hs-CRP and PLT between the two groups were compared. Changes of the three indicators in sepsis were also observed after treatment. The diagnostic value of indicators for neonatal sepsis was evaluated by receiver operating characteristic (ROC) curve. Results: In sepsis group, RIP3 and hs-CRP levels were significantly higher than those in control group (RIP3, p ＜ 0.0001; hs-CRP, p ＜ 0.0001), and PLT level was significantly lower than that in control group (p＜0.0001). After treatment, RIP3 and hs-CRP levels among septic survivors had a significant decrease (p＜0.0001) and PLT level had a significant improvement (p=0.0028). With RIP3＞15464.72 pg/mL, CRP>3.24 mg/L, PLT<205.00×10 9 /L as the positive criteria, the sensitivity of the three indicators in the diagnosis of neonatal sepsis was 68.8%, 64.5%, 59.1%, and the specificity was 91.4%, 82.8%, 79.6%, respectively. The combination of RIP3, CRP and PLT showed 76.3% sensitivity and 94.6% sensitivity. Conclusions: RIP3 may attribute to the early diagnosis and understanding therapeutic effect of neonatal sepsis. The combined detection of RIP3, CRP and PLT may be more effective than individual ones in the diagnosis of neonatal sepsis." @default.
• W3136086176 created "2021-03-29" @default.
• W3136086176 creator A5012325433 @default.
• W3136086176 creator A5020951392 @default.
• W3136086176 creator A5024976083 @default.
• W3136086176 creator A5034925351 @default.
• W3136086176 creator A5048530877 @default.
• W3136086176 creator A5059281058 @default.
• W3136086176 creator A5060045196 @default.
• W3136086176 creator A5065544513 @default.
• W3136086176 creator A5091136233 @default.
• W3136086176 date "2021-03-17" @default.
• W3136086176 modified "2023-09-26" @default.
• W3136086176 title "The Potential Value of Plasma Receptor Interacting Protein 3 for Neonatal Sepsis Diagnosis" @default.
• W3136086176 cites W1759752074 @default.
• W3136086176 cites W1803162504 @default.
• W3136086176 cites W1972791493 @default.
• W3136086176 cites W1985231277 @default.
• W3136086176 cites W1997183854 @default.
• W3136086176 cites W2033968700 @default.
• W3136086176 cites W2059738518 @default.
• W3136086176 cites W2060274331 @default.
• W3136086176 cites W2076590961 @default.
• W3136086176 cites W2121365919 @default.
• W3136086176 cites W2164990391 @default.
• W3136086176 cites W2165330403 @default.
• W3136086176 cites W2324411687 @default.
• W3136086176 cites W2605394509 @default.
• W3136086176 cites W2615250038 @default.
• W3136086176 cites W2768664744 @default.
• W3136086176 cites W2790636557 @default.
• W3136086176 cites W2793567690 @default.
• W3136086176 cites W2800533041 @default.
• W3136086176 cites W2814347658 @default.
• W3136086176 cites W2901130621 @default.
• W3136086176 cites W2912065765 @default.
• W3136086176 cites W2919126765 @default.
• W3136086176 cites W3003764017 @default.
• W3136086176 cites W3103091581 @default.
• W3136086176 doi "https://doi.org/10.21203/rs.3.rs-300543/v1" @default.
• W3136086176 hasPublicationYear "2021" @default.
• W3136086176 type Work @default.
• W3136086176 sameAs 3136086176 @default.
• W3136086176 citedByCount "0" @default.
• W3136086176 crossrefType "posted-content" @default.
• W3136086176 hasAuthorship W3136086176A5012325433 @default.
• W3136086176 hasAuthorship W3136086176A5020951392 @default.
• W3136086176 hasAuthorship W3136086176A5024976083 @default.
• W3136086176 hasAuthorship W3136086176A5034925351 @default.
• W3136086176 hasAuthorship W3136086176A5048530877 @default.
• W3136086176 hasAuthorship W3136086176A5059281058 @default.
• W3136086176 hasAuthorship W3136086176A5060045196 @default.
• W3136086176 hasAuthorship W3136086176A5065544513 @default.
• W3136086176 hasAuthorship W3136086176A5091136233 @default.
• W3136086176 hasBestOaLocation W31360861761 @default.
• W3136086176 hasConcept C126322002 @default.
• W3136086176 hasConcept C203014093 @default.
• W3136086176 hasConcept C2775953899 @default.
• W3136086176 hasConcept C2776914184 @default.
• W3136086176 hasConcept C2778384902 @default.
• W3136086176 hasConcept C2781195455 @default.
• W3136086176 hasConcept C58471807 @default.
• W3136086176 hasConcept C71924100 @default.
• W3136086176 hasConcept C90924648 @default.
• W3136086176 hasConceptScore W3136086176C126322002 @default.
• W3136086176 hasConceptScore W3136086176C203014093 @default.
• W3136086176 hasConceptScore W3136086176C2775953899 @default.
• W3136086176 hasConceptScore W3136086176C2776914184 @default.
• W3136086176 hasConceptScore W3136086176C2778384902 @default.
• W3136086176 hasConceptScore W3136086176C2781195455 @default.
• W3136086176 hasConceptScore W3136086176C58471807 @default.
• W3136086176 hasConceptScore W3136086176C71924100 @default.
• W3136086176 hasConceptScore W3136086176C90924648 @default.
• W3136086176 hasLocation W31360861761 @default.
• W3136086176 hasOpenAccess W3136086176 @default.
• W3136086176 hasPrimaryLocation W31360861761 @default.
• W3136086176 hasRelatedWork W10293907 @default.
• W3136086176 hasRelatedWork W12299610 @default.
• W3136086176 hasRelatedWork W13087184 @default.
• W3136086176 hasRelatedWork W13777102 @default.
• W3136086176 hasRelatedWork W14323734 @default.
• W3136086176 hasRelatedWork W15835446 @default.
• W3136086176 hasRelatedWork W2787473 @default.
• W3136086176 hasRelatedWork W2878464 @default.
• W3136086176 hasRelatedWork W8669634 @default.
• W3136086176 hasRelatedWork W9360305 @default.
• W3136086176 isParatext "false" @default.
• W3136086176 isRetracted "false" @default.
• W3136086176 magId "3136086176" @default.
• W3136086176 workType "article" @default.