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- W3136105419 abstract "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiologic agent of the COVID-19 pandemic. The development of a high-throughput pseudovirus neutralization assay is critical for the development of vaccines and immune-based therapeutics. In this study, we show that deletion of the cytoplasmic tail of the SARS-CoV-2 spike leads to pseudoviruses with enhanced infectivity. This SΔCT13-based pseudovirus neutralization assay should be broadly useful for the field." @default.
- W3136105419 created "2021-03-29" @default.
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- W3136105419 date "2021-05-10" @default.
- W3136105419 modified "2023-10-18" @default.
- W3136105419 title "Deletion of the SARS-CoV-2 Spike Cytoplasmic Tail Increases Infectivity in Pseudovirus Neutralization Assays" @default.
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- W3136105419 doi "https://doi.org/10.1128/jvi.00044-21" @default.
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