FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3136110066> ?p ?o ?g. }

• W3136110066 endingPage "2598" @default.
• W3136110066 startingPage "2587" @default.
• W3136110066 abstract "BackgroundFish could play a role in preventing type 2 diabetes (T2D) but there has been little specification about the type of fish and the preventive mechanism involved in its health claim. The sardine is a source of omega-3 and taurine that, in isolation or in synergy, would produce T2D-delaying through different molecular mechanism.HypothesisThe consumption of twice a week of sardine, during one year would reduce T2D-developing risk in a population with prediabetes (preDM) and old age.Design152 subjects with fasting glucose between 100-124 mg/dL aged ≥65 yo were recruited from three primary care centers in Barcelona and were randomly distributed among two interventional groups: control group (CG) and sardine group (SG). Both groups received same T2D-prevention nutritional during a year but only SG had to add 200 g of sardine per week. All variables were collected before to start and at the end of the diet. (ClinicalTrials.gov: NCT03557541).Results152 people were randomized into CG (n=77) and SG (n=75) with 18 and 12 drop outs respectively. Subjects in SG, significantly compared to CG, decreased percentage classified-individuals in a very high risk group to develop T2D according to FINDRISC (p=0.035). In addition to increasing HDL-cholesterol and adiponectin and decreasing triglycerides (p<0.05) and blood pressure (<0.05), SG showed a lower HOMA-IR (p=0.032). The consumption of sardine characteristics nutrients as omega-3, EPA and DHA, vitamin D, fluorine and taurine were higher for SG (p<0.05). These results agreed with the increased of taurine, fatty acid (FA) omega-3 and bile acids circulating metabolites (p<0.05). Changes erythrocyte membrane FA were detected only in SG with a decrease of 5 omega-6 FA (p<0.001) and an increase of 3 omega-3 FA types (p<0.001).ConclusionWe conclude that a year T2D-prevention diet with sardine supplementation has a greater protective effect against developing T2D and CV events. Fish could play a role in preventing type 2 diabetes (T2D) but there has been little specification about the type of fish and the preventive mechanism involved in its health claim. The sardine is a source of omega-3 and taurine that, in isolation or in synergy, would produce T2D-delaying through different molecular mechanism. The consumption of twice a week of sardine, during one year would reduce T2D-developing risk in a population with prediabetes (preDM) and old age. 152 subjects with fasting glucose between 100-124 mg/dL aged ≥65 yo were recruited from three primary care centers in Barcelona and were randomly distributed among two interventional groups: control group (CG) and sardine group (SG). Both groups received same T2D-prevention nutritional during a year but only SG had to add 200 g of sardine per week. All variables were collected before to start and at the end of the diet. (ClinicalTrials.gov: NCT03557541). 152 people were randomized into CG (n=77) and SG (n=75) with 18 and 12 drop outs respectively. Subjects in SG, significantly compared to CG, decreased percentage classified-individuals in a very high risk group to develop T2D according to FINDRISC (p=0.035). In addition to increasing HDL-cholesterol and adiponectin and decreasing triglycerides (p<0.05) and blood pressure (<0.05), SG showed a lower HOMA-IR (p=0.032). The consumption of sardine characteristics nutrients as omega-3, EPA and DHA, vitamin D, fluorine and taurine were higher for SG (p<0.05). These results agreed with the increased of taurine, fatty acid (FA) omega-3 and bile acids circulating metabolites (p<0.05). Changes erythrocyte membrane FA were detected only in SG with a decrease of 5 omega-6 FA (p<0.001) and an increase of 3 omega-3 FA types (p<0.001). We conclude that a year T2D-prevention diet with sardine supplementation has a greater protective effect against developing T2D and CV events." @default.
• W3136110066 created "2021-03-29" @default.
• W3136110066 creator A5021695418 @default.
• W3136110066 creator A5051735432 @default.
• W3136110066 creator A5052442184 @default.
• W3136110066 creator A5061297180 @default.
• W3136110066 creator A5080459428 @default.
• W3136110066 creator A5088522161 @default.
• W3136110066 date "2021-05-01" @default.
• W3136110066 modified "2023-10-12" @default.
• W3136110066 title "Type 2 diabetes preventive effects with a 12-months sardine-enriched diet in elderly population with prediabetes: An interventional, randomized and controlled trial" @default.
• W3136110066 cites W1749316807 @default.
• W3136110066 cites W1863654876 @default.
• W3136110066 cites W1891939305 @default.
• W3136110066 cites W1965952610 @default.
• W3136110066 cites W1983782600 @default.
• W3136110066 cites W1985954634 @default.
• W3136110066 cites W1987100478 @default.
• W3136110066 cites W1988385409 @default.
• W3136110066 cites W1990994166 @default.
• W3136110066 cites W1998007271 @default.
• W3136110066 cites W2000910089 @default.
• W3136110066 cites W2007543394 @default.
• W3136110066 cites W2011256163 @default.
• W3136110066 cites W2017771330 @default.
• W3136110066 cites W2019216107 @default.
• W3136110066 cites W2021628915 @default.
• W3136110066 cites W2025830846 @default.
• W3136110066 cites W2026448309 @default.
• W3136110066 cites W2032980112 @default.
• W3136110066 cites W2033393111 @default.
• W3136110066 cites W2034673008 @default.
• W3136110066 cites W2039649808 @default.
• W3136110066 cites W2054448290 @default.
• W3136110066 cites W2056232359 @default.
• W3136110066 cites W2064358352 @default.
• W3136110066 cites W2067801910 @default.
• W3136110066 cites W2073790750 @default.
• W3136110066 cites W2073895687 @default.
• W3136110066 cites W2074269574 @default.
• W3136110066 cites W2078993054 @default.
• W3136110066 cites W2080908766 @default.
• W3136110066 cites W2090891305 @default.
• W3136110066 cites W2095552627 @default.
• W3136110066 cites W2099491564 @default.
• W3136110066 cites W2104468045 @default.
• W3136110066 cites W2107073645 @default.
• W3136110066 cites W2107956878 @default.
• W3136110066 cites W2108948907 @default.
• W3136110066 cites W2109833610 @default.
• W3136110066 cites W2114104256 @default.
• W3136110066 cites W2122367003 @default.
• W3136110066 cites W2124124606 @default.
• W3136110066 cites W2126581925 @default.
• W3136110066 cites W2127238287 @default.
• W3136110066 cites W2127261185 @default.
• W3136110066 cites W2130022947 @default.
• W3136110066 cites W2130099681 @default.
• W3136110066 cites W2131909681 @default.
• W3136110066 cites W2135523822 @default.
• W3136110066 cites W2141414207 @default.
• W3136110066 cites W2143383690 @default.
• W3136110066 cites W2147273777 @default.
• W3136110066 cites W2155933627 @default.
• W3136110066 cites W2157608134 @default.
• W3136110066 cites W2158958532 @default.
• W3136110066 cites W2160995945 @default.
• W3136110066 cites W2161096570 @default.
• W3136110066 cites W2167371554 @default.
• W3136110066 cites W2188678714 @default.
• W3136110066 cites W2194701238 @default.
• W3136110066 cites W2227610719 @default.
• W3136110066 cites W2268867855 @default.
• W3136110066 cites W2315929780 @default.
• W3136110066 cites W2319041462 @default.
• W3136110066 cites W2338627428 @default.
• W3136110066 cites W2404504991 @default.
• W3136110066 cites W2535096797 @default.
• W3136110066 cites W2588130051 @default.
• W3136110066 cites W2591880667 @default.
• W3136110066 cites W2741501019 @default.
• W3136110066 cites W2752002135 @default.
• W3136110066 cites W2754394790 @default.
• W3136110066 cites W2766147673 @default.
• W3136110066 cites W2796144553 @default.
• W3136110066 cites W2895911941 @default.
• W3136110066 cites W2897896320 @default.
• W3136110066 cites W2919006174 @default.
• W3136110066 cites W3085373585 @default.
• W3136110066 cites W3119062329 @default.
• W3136110066 cites W4239111638 @default.
• W3136110066 doi "https://doi.org/10.1016/j.clnu.2021.03.014" @default.
• W3136110066 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33932804" @default.
• W3136110066 hasPublicationYear "2021" @default.
• W3136110066 type Work @default.
• W3136110066 sameAs 3136110066 @default.
• W3136110066 citedByCount "8" @default.
• W3136110066 countsByYear W31361100662022 @default.

• next