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- W3136115216 abstract "The global use of alcohol-based hand sanitizers (ABHS) as an important means of controlling the transmission of infectious disease has increased significantly as governments and public health agencies across the world advocated hand hygiene as a preventative measure during the COVID-19 pandemic. Although the performance of these products is most commonly defined as a function of their alcohol concentration, they are multifaceted products in which an interplay of several factors is important in determining efficacy. This paper discusses the interplay between ABHS input (formulation) factors and output (product performance) factors in the context of a multidimensional perspective using a novel representative paradigm. In the model, represented in the form of a three-dimensional tetrahedron, each of the faces represents inputs in the manufacturing of the ABHS product, which are the type and amount of alcohol, the inactive ingredients, the formulation and the manufacturing practices. The four corners of the tetrahedron represent the product performance factors which include product efficacy, sensory characteristics, usage and compliance and product safety. The multidimensional approach to the formulation and evaluation of ABHS shows that several factors contribute to the effectiveness and utility of these products. The paradigm provides a useful framework for manufacturers of ABHS and related healthcare products." @default.
- W3136115216 created "2021-03-29" @default.
- W3136115216 creator A5035488334 @default.
- W3136115216 creator A5046879738 @default.
- W3136115216 date "2021-03-19" @default.
- W3136115216 modified "2023-09-24" @default.
- W3136115216 title "Alcohol-Based Hand Sanitizers in COVID-19 Prevention: A Multidimensional Perspective" @default.
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- W3136115216 doi "https://doi.org/10.3390/pharmacy9010064" @default.
- W3136115216 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8006002" @default.
- W3136115216 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33808754" @default.
- W3136115216 hasPublicationYear "2021" @default.
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