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- W3136121359 abstract "Renal failure or acute/chronic kidney damage may present as a clinical manifestation of rheumatic diseases. In addition treatment with DMARDs or biologic drugs may induce nephrotoxicity. In this case-based review, we present two patients with SpA under anti-TNF-α treatment admitted to our hospital because of renal failure and proteinuria. We review previously published yet isolated cases of TNF-α blocker-induced glomerular disease in patients with SpA. Renal manifestations are occasionally seen in patients with ankylosing spondylitis and psoriatic arthritis with IgA nephropathy being the most common of them. Anti-TNF-α agents although reportedly used for the treatment of glomerular nephropathy as a disease manifestation, they have been considered responsible for provoking renal damage in some cases. A diagnostic approach for patients with SpA treated with anti-TNF-α agents presenting with renal manifestations is proposed herein." @default.
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- W3136121359 date "2021-03-01" @default.
- W3136121359 modified "2023-10-18" @default.
- W3136121359 title "Glomerulonephritis in Two Patients with SpA Treated with TNF-α Blockers and a Review of the Literature" @default.
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- W3136121359 doi "https://doi.org/10.2147/btt.s297712" @default.
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